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Title A nano-biosensor for DNA sequence detection using absorption spectra of SWNT-DNA composite
Authors Bansal, J.
Singh, I.
Mathur, N.
Aneja, A.
Bhatnagar, P.K.
Mathur, P.C.
ORCID
Keywords biosensor
биодатчик
біодатчик
энергия связи экситона
енергія зв'язку екситона
exciton binding energy
Type Article
Date of Issue 2011
URI http://essuir.sumdu.edu.ua/handle/123456789/22121
Publisher Видавництво СумДУ
License
Citation A nano-biosensor for DNA sequence detection using absorption spectra of SWNT-DNA composite [Текст] / J. Bansal, I. Singh, N. Mathur et al. // Journal of Nano- and Electronic Physics. — 2011. — Vol.3, № 1, Part IV : Proceedings of the International Symposium on Semiconductor Materials and Devices (ISSMD-2011), Vadodara, India, 28-30 January 2011. — P. 776-782.
Abstract biosensor based on Single Walled Carbon Nanotube (SWNT)-Poly (GT)n ssDNA hybrid has been developed for medical diagnostics. The absorption spectrum of this assay is determined with the help of a Shimadzu UV-VIS-NIR spectrophotometer. Two distinct bands each containing three peaks corresponding to first and second van Hove singularities in the density of states of the nanotubes were observed in the absorption spectrum. When a single-stranded DNA (ssDNA) having a sequence complementary to probic DNA is added to the ssDNA-SWNT conjugates, hybridization takes place, which causes the red shift of absorption spectrum of nanotubes. On the other hand, when the DNA is noncomplementary, no shift in the absorption spectrum occurs since hybridization between the DNA and probe does not take place. The red shifting of the spectrum is considered to be due to change in the dielectric environment around nanotubes. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/22121
Appears in Collections: Журнал нано- та електронної фізики (Journal of nano- and electronic physics)

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