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Title Application of Chitosan / Cyclodextrin Nanoparticles for Tissue Glutathione Delivery
Authors Rotar, O.V.
Rotar, V.I.
ORCID
Keywords Glutathion
Nanoparticles
Cyclodextrin
Chitosan
Type Conference Papers
Date of Issue 2013
URI http://essuir.sumdu.edu.ua/handle/123456789/35422
Publisher Sumy State University
License
Citation Rotar, O.V. Application of Chitosan / Cyclodextrin Nanoparticles for Tissue Glutathione Delivery [Текст] / O.V. Rotar, V.I. Rotar // Nanomaterials: Applications & Properties (NAP-2013) : 2-nd International conference, Alushta, the Crimea, September 17-22, 2012 / Edited by: A. Pogrebnjak. - Sumy : Sumy State University, 2013. - V.2, No4. - 04NABM07
Abstract The aim of this study was to investigate an ability of chitosan nanoparticles for tissue delivery of the peptide glutathione. Formulations composed of chitosan or chitosan plus cyclodextrin-beta comlex were prepared. Reduced glutathione was loaded and delivered to mucosal layer of small intestine after ischemia-reperfusion injury more efficiently in chitosan/cyclodextrin-beta nanoparticles. From the data obtained, we believe that chitosan / cyclodextrin nanoparticles can be used for the oral administration of glutathione and other small peptides. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/35422
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