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Title | Peculiarities of sickle cell anemia in patients with malaria in Africa |
Authors |
Okoye, Chukwuebuka D.
Bamisile, Ayodeji Segun |
ORCID | |
Keywords |
аутосомно-рецесивні захворювання аутосомно-рецессивные заболевания autosomal recessive disease малярія малярия malaria |
Type | Conference Papers |
Date of Issue | 2016 |
URI | http://essuir.sumdu.edu.ua/handle/123456789/47876 |
Publisher | Sumy State University |
License | |
Citation | Okoye, Chukwuebuka D. Peculiarities of sickle cell anemia in patients with malaria in Africa [Текст] / Chukwuebuka D. Okoye, Ayodeji Segun Bamisile; Scientific adviser V.V. Kmyta // Актуальні питання теоретичної та практичної медицини : збірник тез доповідей ІV Міжнародної науково-практичної конференції студентів та молодих вчених, м. Суми, 21-22 квітня 2016 р. / Н.В. Деміхова. – Суми : СумДУ, 2016. – Т.2. – P. 141. |
Abstract |
Background. Sickle cell anemia is an autosomal recessive disease caused by a single point mutation in nucleobase sequence of chromosome 11 with substitution of glutamic acid by valine and formation of HbS is widespread in mainly African countries with prevalence of 20% - 30% in Cameroon, Republic of Congo, Gabon, Ghana, Nigeria and 45% in Uganda. Malaria on the other hand is an infection caused by a parasite (Plasmodium sp.) that is transmitted to humans by female anopheles mosquito and is prevalent in tropical and subtropical regions of Africa due to increased rainfall, constant high temperatures and high humidity. |
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