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Title | Biomechanical properties studying of atherosclerotic aortic wall with micro and macrocalcifications |
Authors |
Moskalenko, Roman Andriiovych
Romaniuk, Anatolii Mykolaiovych Zakorko, Inna-Marharyta Serhiivna Levchenko, Dmytro Oleksiiovych Lyndin, Mykola Serhiiovych Piddubnyi, Artem Mykhailovych Sikora, Vladyslav Volodymyrovych |
ORCID |
http://orcid.org/0000-0002-2342-0337 http://orcid.org/0000-0003-2560-1382 http://orcid.org/0000-0003-4385-3903 http://orcid.org/0000-0002-6508-0131 http://orcid.org/0000-0002-4147-6879 |
Keywords |
аорта аорта aorta біомінералізація биоминерализация biomineralization біомеханічні особливості биомеханические особенности biomechanical properties |
Type | Conference Papers |
Date of Issue | 2017 |
URI | http://essuir.sumdu.edu.ua/handle/123456789/64315 |
Publisher | Springer |
License | |
Citation | Biomechanical properties studying of atherosclerotic aortic wall with micro and macrocalcifications / R. Moskalenko, A. Romaniuk, I.-M. Zakorko [et al.] // Virchows Arch. - 2017. - Vol. 471, Suppl. 1. – P. 173. |
Abstract |
Objective: In the aortic wall calcification occurs as a pattern of micro- and macrocalcification changing significantly aortic wall biomechanical properties. The aim of the work is biom echanical properties
studying of aortic wall in the conditions of macro and microcalcification.
Method: 18 atherosclerotic aorta tissue samples with histologically verified different calcification patterns were studied. The samples were divided into 3 groups: control - without calcification
man ifistation (6), with micro calcification - calcium deposits to
4.99 mm (6), macrocalcification - calcifications <5 mm (6). Hydrostatic test stand was to study tissue samples strength, using the principle of equal distribution of pressure and its gradual increase
on the sample surface. The experimental stand consists o f metal container, filled with liquid under pressure o f 5-8 bar, pressure conduit, a regulating valve, model m anom eter (accuracy class 0.4) and test
chamber with fastening mechanisms o f aorta samples. Moments of aortic w all ru p tu re and th e manometer index were fixed on the camera.
Results: For the control group pressure o f aorta wall rupture was 389,19 ± 60,11 kPa. For aorta with microcalcifications rupture pressure w as 1 2 8 ,6 3 ± 2 5 ,3 4 k P a , at th e sam e tim e , th e a o r ta w ith macrocalcification patterns rupture pressure was 344,0 ± 35,88 kPa.
Conclusion: Aorta samples with macrocalcifications are significantly more stable to h y d r o d y n a m ic p r e s s u r e , tha n a o r ta w ith microcalcifications (p < 0.01). Moreover, the resistance to pressure in the case o f macrocalcifications is not significantly different from the control group (p> 0.05) |
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Biomech_properties_calcificats_Moskalenko.pdf | 527.76 kB | Adobe PDF | -1332084499 |
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