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Title HIFU Transducers Designs and Ultrasonic Treatment Methods for Biological Tissues
Authors Rybyanets, A.N.
Shvetsov, I.A.
Shcherbinin, S.A.
Petrova, E.I.
Shvetsova, N.A.
ORCID
Keywords ultrasonic transducer
high intensity focused ultrasound
acoustic field
theoretical modeling
hemostasis
porous piezoceramics
deep arterial bleeding
Type Article
Date of Issue 2018
URI http://essuir.sumdu.edu.ua/handle/123456789/68671
Publisher Sumy State University
License
Citation HIFU Transducers Designs and Ultrasonic Treatment Methods for Biological Tissues [Текст] / A.N. Rybyanets, I.A. Shvetsov, S.A. Shcherbinin [et al.] // Журнал нано- та електронної фізики. - 2018. - Т. 10, № 2. - 02043. - DOI: 10.21272/jnep.10(2).02043.
Abstract The purpose of this study was to evaluate the feasibility of high intensity focused ultrasound (HIFU) for ultrasonic treatment of biological tissues, particularly, for hemostasis of deep arterial bleeding. The results of designing, modeling and evaluation of an ultrasound applicator capable of creating thermal lesions in the arterial vessels were presented. New effective HIFU transducers designs and ultrasonic methods for stopping deep arterial bleeding were developed and estimated. Mathematical modeling of the HIFU transducers and acoustic fields were performed. The experiments were made on acoustic vascular phantoms as well as on lamb’s femoral artery at a standard protocol. During ultrasound exposure, arterial blood flow was temporarily stopped using intravascular balloon. Postponed hemostasis was observed at lamb’s femoral artery experiments for all HIFU treatments. It was demonstrated that HIFU can be used to stop active bleeding from vascular injuries including punctures and lacerations. The results of theoretical modeling, acoustic measurements, and in vivo vascular experiments prove the efficacy, safety and selectivity of developed HIFU transducers and methods used for enhancing of tissue lysis and hemostasis.
Appears in Collections: Журнал нано- та електронної фізики (Journal of nano- and electronic physics)

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China China
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19907053
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19907051
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76829670
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