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Title | HIFU Transducers Designs and Ultrasonic Treatment Methods for Biological Tissues |
Authors |
Rybyanets, A.N.
Shvetsov, I.A. Shcherbinin, S.A. Petrova, E.I. Shvetsova, N.A. |
ORCID | |
Keywords |
ultrasonic transducer high intensity focused ultrasound acoustic field theoretical modeling hemostasis porous piezoceramics deep arterial bleeding |
Type | Article |
Date of Issue | 2018 |
URI | http://essuir.sumdu.edu.ua/handle/123456789/68671 |
Publisher | Sumy State University |
License | Copyright not evaluated |
Citation | HIFU Transducers Designs and Ultrasonic Treatment Methods for Biological Tissues [Текст] / A.N. Rybyanets, I.A. Shvetsov, S.A. Shcherbinin [et al.] // Журнал нано- та електронної фізики. - 2018. - Т. 10, № 2. - 02043. - DOI: 10.21272/jnep.10(2).02043. |
Abstract |
The purpose of this study was to evaluate the feasibility of high intensity focused ultrasound (HIFU)
for ultrasonic treatment of biological tissues, particularly, for hemostasis of deep arterial bleeding. The
results of designing, modeling and evaluation of an ultrasound applicator capable of creating thermal
lesions in the arterial vessels were presented. New effective HIFU transducers designs and ultrasonic
methods for stopping deep arterial bleeding were developed and estimated. Mathematical modeling of the
HIFU transducers and acoustic fields were performed. The experiments were made on acoustic vascular
phantoms as well as on lamb’s femoral artery at a standard protocol. During ultrasound exposure, arterial
blood flow was temporarily stopped using intravascular balloon. Postponed hemostasis was observed at
lamb’s femoral artery experiments for all HIFU treatments. It was demonstrated that HIFU can be used to
stop active bleeding from vascular injuries including punctures and lacerations. The results of theoretical
modeling, acoustic measurements, and in vivo vascular experiments prove the efficacy, safety and
selectivity of developed HIFU transducers and methods used for enhancing of tissue lysis and hemostasis. |
Appears in Collections: |
Журнал нано- та електронної фізики (Journal of nano- and electronic physics) |
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Rybyanets_transducers.pdf | 259.07 kB | Adobe PDF | 116643794 |
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