Association of Arg389Gly polymorphism of ADRβ1 gene and T393C of GNAS1 gene with risk of development of acute coronary syndrome in patients with arterial hypertension

Dudchenko, Iryna Oleksandrivna; Prystupa, Liudmyla Nykodymivna; Fadieieva, Hanna Anatoliivna; Moіseienko, Iryna Olehivna; Bondarkova, Anna Mykolaivna; Kuchma, Nataliia Hryhorivna; Orlovskyi, Oleksandr Viktorovych; Moiseyenko, Iryna Olehivna

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Title	Association of Arg389Gly polymorphism of ADRβ1 gene and T393C of GNAS1 gene with risk of development of acute coronary syndrome in patients with arterial hypertension
Authors	Dudchenko, Iryna Oleksandrivna Prystupa, Liudmyla Nykodymivna Fadieieva, Hanna Anatoliivna Moіseienko, Iryna Olehivna Bondarkova, Anna Mykolaivna Kuchma, Nataliia Hryhorivna Orlovskyi, Oleksandr Viktorovych Moiseyenko, Iryna Olehivna
ORCID	http://orcid.org/0000-0002-7038-4455 http://orcid.org/0000-0002-6454-9831 http://orcid.org/0000-0003-3056-5793 http://orcid.org/0000-0002-6748-9774 http://orcid.org/0000-0003-0036-4915 http://orcid.org/0000-0001-7679-2858 http://orcid.org/0000-0003-1851-4598
Keywords	артеріальна гіпертензія артериальная гипертензия arterial hypertension гострий коронарний синдром острый коронарный синдром acute coronary syndrome поліморфізм генів полиморфизм генов gene polymorphism
Type	Article
Date of Issue	2020
URI	https://essuir.sumdu.edu.ua/handle/123456789/77802
Publisher	Lithuanian University of Health Sciences
License
Citation	Association of Arg389Gly polymorphism of ADRβ1 gene and T393C of GNAS1 gene with risk of development of acute coronary syndrome in patients with arterial hypertension / I.O. Dudchenko, L.N. Prystupa, H.A. Fadieieva, et al. // Medicina (Kaunas). - 2020. - V. 56. - P. 202.
Abstract	In our study, we discovered the relationship of the Arg389Gly polymorphism of the ADRβ1 gene and the T393C polymorphism of the GNAS1 gene with the risk of ACS development in the Ukrainian population. Carriers of the Arg389 allele of the polymorphism of the ADRβ1 gene and the C393 allele of the polymorphism of the GNAS1 gene showed a higher risk of ACS development relative to the opposite alleles in these gene polymorphisms.
Appears in Collections:	Наукові видання (НН МІ)