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Title | Association of the C+70G polymorphic site of the ednra gene with large artery stroke development in smokers and non-smokers |
Authors |
Oleshko, Tetiana Bohdanivna
![]() Kharchenko, A.M. Shchepet, Yu.Ye. Oleshko, Tetiana Mykolaivna ![]() |
ORCID |
http://orcid.org/0000-0002-5909-5812 http://orcid.org/0000-0002-2229-2839 |
Keywords |
інсульт инсульт stroke |
Type | Conference Papers |
Date of Issue | 2019 |
URI | https://essuir.sumdu.edu.ua/handle/123456789/80872 |
Publisher | Sumy State University |
License | Copyright not evaluated |
Citation | Association of the C+70G polymorphic site of the ednra gene with large artery stroke development in smokers and non-smokers / T.B. Oleshko, A.M. Kharchenko, Yu.Ye. Shchepet, T.M. Oleshko // International Scientific and Practical Conference of Students, Postgraduates and Young Scientists. - Sumy, 2019. October 16-18. - P. 133 . |
Abstract |
It is known that endothelial dysfunction plays a leading role in the pathogenesis of vascular brain disorders. One of the driving factors that contributes to the development of endothelial dysfunction is a potent endogenous vasoconstrictor ‒ endothelin-1, which exerts its effects through interaction with a specific type A receptor. Given that smoking is an important risk factor for endothelial disorders and stroke, the relevance of its study is undeniable. |
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