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Title | The lead content in biological media term infants with hypoxic-ischemic CNS |
Authors |
Kasian, Svitlana Mykolaivna
Loboda, Andrii Mykolaiovych Smiian, Oleksandr Ivanovych Popov, Serhii Vitaliiovych Petrashenko, Viktoriia Oleksandrivna Zahorodnii, M. P. Zaitsev, Ihor Eduardovych Redko, Olena Kostiantynivna Shkolna, Iryna Ivanivna |
ORCID |
http://orcid.org/0000-0002-1206-5739 http://orcid.org/0000-0002-5400-773X http://orcid.org/0000-0001-8225-0975 http://orcid.org/0000-0002-1789-1474 http://orcid.org/0000-0002-4648-8916 http://orcid.org/0000-0002-8248-7216 http://orcid.org/0000-0001-5501-829X http://orcid.org/0000-0001-6756-0158 |
Keywords |
lead hypoxia full-term newborn |
Type | Article |
Date of Issue | 2021 |
URI | https://essuir.sumdu.edu.ua/handle/123456789/83226 |
Publisher | Bangladesh Academy of Sciences |
License | Creative Commons Attribution 4.0 International License |
Citation | Kasian, S., Loboda, A., Smiyan, O., Popov, S., Petrashenko, V., Zahorodnii, M., Zaitsev, I., Redko, O., & Shkolna, I. (2021). The lead content in biological media term infants with hypoxic-ischemic CNS. Bangladesh Journal of Medical Science, 20(2), 330-333. https://doi.org/10.3329/bjms.v20i2.51543 |
Abstract |
Introduction: The frequency of births of infants with perinatal pathology has increased in
recent years. The aim of this study is to determination of lead content in the biomedias of
newborns with hypoxic-ischemic damage of the central nervous system (CNS). Materials and
Methods: We studied influence of the lead content in children, which were born with hypoxicischemic lesion CNS (HIL CNS). Determination of this microelement was carried out in the
blood serum, erythrocytes and urine of 30 newborn infants which were suffered from asphyxia
after birth. The comparison group consisted of 30 healthy full-term newborns. Results: In the
biomedias of children with the HIL of the central nervous system, a toxic trace element of lead
has been identified which is poorly retained in the placenta, so the fetus is more vulnerable to
its toxic effects in the prenatal period. In the article the features of the lead content in serum,
erythrocytes and urine in term infants which were born with hypoxic-ischemic CNS lesions are
investigated. This group of subjects had increased serum and erythrocyte concentration of lead.
The high content of lead in the erythrocytes of children with hypoxia which is already at birth
may indicate a transplacental penetration of this toxic trace element and the possibility of its
negative impact on the course of pregnancy. Conclusions: The prognostic significance of the
lead content was high. Thus, the informative index (Ī) for lead content in serum is 7.40, and the
prognostic factor (PC) is + 15.1. As for the prognostic value of the lead content in erythrocytes
and urine, very high predictor properties are established for them: Ī = 7.44; PC = + 7.0 and Ī =
13.42; PC = + 16.1 respectively. |
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Kasian_et.al._hypoxia_2021.pdf | 323.86 kB | Adobe PDF | -285860457 |
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