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Title | Influence of technological manufacturing conditions on the porosity of calcium-phosphate scaffolds |
Authors |
Chernobrovchenko, V.S.
Diadiura, Kostiantyn Oleksandrovych Balynskyi, M. Panda A., A. |
ORCID |
http://orcid.org/0000-0002-7575-9711 |
Keywords |
porosity porosity influence hydroxyapatite bone substitute relationship osseointegration |
Type | Article |
Date of Issue | 2021 |
URI | https://essuir.sumdu.edu.ua/handle/123456789/85350 |
Publisher | Sumy State University |
License | Creative Commons Attribution - NonCommercial - ShareAlike 4.0 International |
Citation | Chernobrovchenko V. S., Dyadyura K. О., Balynskyi M., Panda A. (2021).Influence of technological manufacturing conditions on the porosity of calcium-phosphate scaffolds. Journal of Engineering Sciences, Vol. 8(1), pp. C18–C28, doi: 10.21272/jes.2021.8(1).c3 |
Abstract |
The implantation of bone substitutes depends on the material’s osteoconductive potential and the
structure's porosity Porosity is a characteristic feature of most materials. The porosity of materials has a strong influence
on some of their properties, both structural and functional. An essential requirement for bone scaffolds is porosity,
which guides cells into their physical structure and supports vascularization. The macroporosity should be large enough
and interdependent for bone ingrowth to occur throughout the entire volume of the implant. The pore size for cell
colonization in bioceramics is approximately 100 μm. Pores larger than this value promote bone growth through the
material. This pore size allows the flow of growth factors and cell adhesion and proliferation, allowing the formation
of new bone and developing the capillary system associated with the ceramic implant. Porosity also affects the rate of
resorption of ceramics: the larger the number of micropores, the higher the dissolution rate. The investigated properties
were elastic moduli, ultimate strength, compressive strength, and average apparent density. The results obtained in this
work are consistent with previous studies, proving the positive role of microporosity in osseointegration and bone
formation. |
Appears in Collections: |
Journal of Engineering Sciences / Журнал інженерних наук |
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