Morphological Peculiarities of Parasitic (Trichosomoides crassicauda) Infection in Rat Urinary Bladder

Sikora, Vladyslav Volodymyrovych; Lyndin, Mykola Serhiiovych; Hyriavenko, Nataliia Ivanivna; Moskalenko, Roman Andriiovych; Lyndina, Yuliia Mykolaivna; Sikora, Kateryna Oleksiivna; Chyzhma, Ruslana Anatoliivna; Diachenko, Olena Olehivna; Romaniuk, Anatolii Mykolaiovych

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Title	Morphological Peculiarities of Parasitic (Trichosomoides crassicauda) Infection in Rat Urinary Bladder
Authors	Sikora, Vladyslav Volodymyrovych Lyndin, Mykola Serhiiovych Hyriavenko, Nataliia Ivanivna Moskalenko, Roman Andriiovych Lyndina, Yuliia Mykolaivna Sikora, Kateryna Oleksiivna Chyzhma, Ruslana Anatoliivna Diachenko, Olena Olehivna Romaniuk, Anatolii Mykolaiovych
ORCID	http://orcid.org/0000-0002-4147-6879 http://orcid.org/0000-0003-4385-3903 http://orcid.org/0000-0002-9805-014X http://orcid.org/0000-0002-2342-0337 http://orcid.org/0000-0002-2132-0965 http://orcid.org/0000-0002-9814-6512 http://orcid.org/0000-0003-2560-1382
Keywords	nematode parasite rat Trichosomoides crassicauda urinary bladder
Type	Article
Date of Issue	2021
URI	https://essuir.sumdu.edu.ua/handle/123456789/85419
Publisher	Sciendo
License	Creative Commons Attribution 4.0 International License
Citation	Sikora V., Lуndіn M., Hyriavenko N., Moskalenko R., Lуndіna Y., Sikora K., Chyzhma R., Diachenko O., Romaniuk A. Morphological peculiarities of parasitic (Trichosomoides crassicauda) infection in rat urinary bladder. Mac Vet Rev 2021; 44 (2): i-ix. https://doi.org/10.2478/macvetrev-2021-0019
Abstract	Trichosomoides crassicauda (T. crassicauda) is a parasite commonly localized in the urinary bladder (UB) of laboratory and wild rats. The presence of these helminths can influence the prediction of pathological changes in the UB. Therefore, the purpose of this research was to make a comprehensive study of the features of the morphological changes in the UB wall of white laboratory rats as a result of T. crassicauda infestation. The study was performed on male rats using histological (Hematoxyline-Eosin and Alcian Blue staining) and immunohistochemical (Ki-67, Hsp70, Hsp90α, CD3 and CD20) methods. T. crassicauda was detected in both urine and UB samples. Morphological changes were observed as disruption in urothelial cell stratification and insignificant proliferative and immune responses in the UB. Increased heat shock protein levels were observed which may suggest a natural body’s resistance to this parasite.
Appears in Collections:	Наукові видання (НН МІ)