Please use this identifier to cite or link to this item:
https://essuir.sumdu.edu.ua/handle/123456789/87770
Or use following links to share this resource in social networks:
Tweet
Recommend this item
Title | Impact of MMP-9 Genetic Polymorphism and Concentration on the Development of Coronary Artery Disease in Ukrainian Population |
Authors |
Pohorielova, Oksana Serhiivna
Korniienko, Viktoriia Volodymyrivna Korniienko, Viktoriia Volodymyrivna Chumachenko, Yaroslav Dmytrovych Obukhova, Olha Anatoliivna Martsovenko, I. Harbuzova, Viktoriia Yuriivna |
ORCID |
http://orcid.org/0000-0003-4077-8637 http://orcid.org/0000-0002-5144-2138 http://orcid.org/0000-0002-4803-5435 http://orcid.org/0000-0002-2104-8412 http://orcid.org/0000-0001-7183-6997 |
Keywords |
coronary artery disease chronic coronary syndrome Ukrainian population |
Type | Article |
Date of Issue | 2022 |
URI | https://essuir.sumdu.edu.ua/handle/123456789/87770 |
Publisher | Hindawi |
License | Creative Commons Attribution 4.0 International License |
Citation | Oksana S. Pogorielova, Viktoriia V. Korniienko, Yaroslav D. Chumachenko, Olha A. Obukhova, Igor Martsovenko, Viktoriia Yu. Harbuzova, "Impact of MMP-9 Genetic Polymorphism and Concentration on the Development of Coronary Artery Disease in Ukrainian Population", Cardiology Research and Practice, vol. 2022, Article ID 2067632, 8 pages, 2022. https://doi.org/10.1155/2022/2067632 |
Abstract |
Coronary artery disease (CAD) is one of the leading causes of death in Europe. It is known that atherosclerosis is the primary risk factor of CAD development. MMP-9 is involved in all stages of atherosclerosis and thus may contribute to CAD emergence. To investigate the influence of MMP-9 on the (CAD) development, 25 patients with intact coronary arteries (CA), 40 patients with acute coronary syndrome (ACS), and 63 patients with chronic coronary syndrome (CCS) were enrolled in the study. Real-time PCR was carried out for genotyping on the rs17567-polymorphic locus, and ELISA study was performed to measure the MMP-9 plasma concentration. It was found the lower risk of MI occurrence for AG-carriers (Pa = 0.023; ORa = 0.299, 95% CI = 0.106–0.848) in Ukrainian population. |
Appears in Collections: |
Наукові видання (НН МІ) |
Views
Australia
1
Côte d’Ivoire
1
Greece
1
Ireland
189579
Japan
1
Romania
1
Singapore
1
Sweden
1
Turkey
1
Ukraine
1089331
United Kingdom
375504
United States
14740350
Unknown Country
19528632
Vietnam
7301
Downloads
Egypt
1
Germany
1
India
1
Ireland
1
Philippines
1
Romania
1
South Africa
1
Turkey
1
Ukraine
3126557
United Arab Emirates
1
United Kingdom
1
United States
14740348
Unknown Country
1
Vietnam
7302
Files
File | Size | Format | Downloads |
---|---|---|---|
Pohorielova_et_al_Coronary_Artery_Disease_2022.pdf | 1.23 MB | Adobe PDF | 17874218 |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.