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Title Alginate-hydroxyapatite Beads for Medical Application
Authors Stanislavov, A.
Sukhodub, L.B.
Yanovska, A.A.
Sukhodub, Leonid Fedorovych  
Kuznetzov, V.N.
Keywords Alginate
Hydroxyapatite
Microspheres
Beads
Type Article
Date of Issue 2014
URI http://essuir.sumdu.edu.ua/handle/123456789/37225
Publisher Sumy State University
License
Citation Proc. NAP 3, 02NNSA15 (2014)
Abstract The paper describes the synthesis and characterization of alginate-hydroxyapatite (Alg/HA) beads that potentially can be used for drug release due to the adsorptive properties of HA and transmission ability of the soluble compounds through the alginate membrane. Calcium Alg/HA beads were manufactured by dropping of the Alg/HA suspension into CaCl2 solution. Morphology and phase composition of obtained Alg/HA beads were investigated. It was shown that alginate macromolecules influence the hydroxyapatite size and morphology. Obtained HA with crystal size 15-30 nm inside alginate beads correspond a bioapatite size therefore are interesting for the tissue engineering. The main features of alginate-controlled crystallization are discussed in order to understand some aspects in composite material design. Insertion of HA into the alginate microcapsules allows use such materials for production of drug release microspheres.
Appears in Collections: Наукові видання (ЕлІТ)

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