Features of acute respiratory viral infections in patients with congenital syndrome of immune-endocrine failure

Abstract

Congenital syndrome of immune-endocrine insufficiency (CSIEI) is the type of constitution that is morphologically characterized by primary hyperplasia of the thymus, generalized hyperplasia of lymphoid tissue, adrenal hypoplasia in combination with various anomalies of cardiovascular, and less frequently of urogenital systems. Features of CSIEI in a functional sense are the failure of infectious and immune violations of adaptation under stress. Endocrine failure, which occurs in patients with CSIEI, usually go unnoticed in the outpatient setting and in the ICU appears addisonian crisis with hypovolemia and shock, which are resistant to treatment. Objective: to develop criteria for lifetime diagnosis and prevention CSIEI.