Cardiovascular risk in patients with chronic obstructive pulmonary disease: management and life quality

Abstract

The article presents the results of a study on the relationship between the level of cardiovascular risk and clinical indicators of the severity of chronic obstructive pulmonary disease (COPD). 52 patients with COPD were examined: the dynamics of forced expiration in the first second, forced vital capacity were analyzed, followed by calculation the ratio of forced expiration in the first second to forced vital capacity. Patients were also stratified by COPD severity groups using the GOLD criteria (2023) and the level of cardiovascular risk determined by the method of SCORE. It has been shown that the rate of COPD exacerbations and the degree of airflow restriction are not only components of COPD severity assessment, but also interrelated with the formation / increase ofcardiovascular risk in patients. In particular, with an increase in the severity of COPD and limiting the air flow rate, a decrease in persons with low and medium cardiovascular risk levels was recorded with a progressive increase in the proportion of patients with high cardiovascular risk. It was found that an increase in the frequency of high cardiovascular risk is determined by the level of forced expiration in the first second and the value of the Gensler index, which should be considered as informative criteria for cardiovascular risk among patients of the GOLD-2 group, while the frequency of exacerbations of COPD is also interrelated with the level of cardiovascular risk. The level of restrictions on daily activities of patients and the clinical severity of COPD are also correlated with the level of cardiovascular risk. The growth of limitations of daily activities and the severity of clinical manifestations of COPD are characterized by a direct correlation with the frequency of high cardiovascular risk, so it was shown a mutually aggravating nature of the clinical course of COPD and the level of cardiovascular risk.