Чижма, Руслана АнатоліївнаЧижма, Руслана АнатольевнаChyzhma, Ruslana AnatoliivnaПіддубний, Артем МихайловичПоддубный, Артем МихайловичPiddubnyi, Artem MykhailovychДанильченко, Сергій МиколайовичДанильченко, Сергей НиколаевичDanylchenko, Serhii MykolaiovychКравцова, Ольга ІванівнаКравцова, Ольга ИвановнаKravtsova, Olha IvanivnaМоскаленко, Роман АндрійовичМоскаленко, Роман АндреевичMoskalenko, Roman Andriiovych2021-09-272021-09-272021Chyzhma, R., Piddubnyi, A., Danilchenko, S., Kravtsova, O., Moskalenko, R. Potential Role of Hydroxyapatite Nanocrystalline for Early Diagnostics of Ovarian Cancer. Diagnostics 2021, 11, 1741. https://doi.org/10.3390/diagnostics111017410000-0002-2342-03370000-0002-6508-0131https://essuir.sumdu.edu.ua/handle/123456789/85468Calcification is one of the clinical and morphological manifestations of ovarian tumors and it begins at the initial stages of carcinogenesis. Thus, this process can be used for the early diagnostics of some malignant ovarian tumors. We compared the results of ultrasound and histology and found that calcifications of a size less than 200 µm are not detected by ultrasound. These calcified structures are round fragile particles of different sizes. In the EDX (Energy-dispersive X-ray spectroscopy) spectra, the main lines were from Ca and P, and the ratio of these elements corresponds to hydroxyapatite. Thus, we established that hydroxyapatite is the main mineral component of ovarian psammoma bodies and could be used for early diagnostics of ovarian malignant neoplasiaenCC BY-NC-ND 4.0гідроксиапатитгидроксиапатитhydroxyapatiteкальцифікатикальцификатыcalcificationрак яєчникарак яичниковovarian cancerрання діагностикаранняя диагностикаearly diagnosticsArticle