Корнiєнко, Вiкторiя ВолодимирiвнаКорниенко, Виктория ВладимировнаKorniienko, Viktoriia VolodymyrivnaОлешко, Олександр МиколайовичОлешко, Александр НиколаевичOleshko, Oleksandr MykolaiovychГусак, Євгенія ВолодимирівнаГусак, Евгения ВладимировнаHusak, Yevheniia VolodymyrivnaДейнека, Володимир МиколайовичДейнека, Владимир НиколаевичDeineka, Volodymyr MykolaiovychГолубнича, Вікторія МиколаївнаГолубничая, Виктория НиколаевнаHolubnycha, Viktoriia MykolaivnaMishchenko, O.Kazek-Kęsik, A.Jakobik-Kolon, A.Пшеничний, Роман МиколайовичПшеничный, Роман НиколаевичPshenychnyi, Roman MykolaiovychLeśniak-Ziółkowska, K.Kalinkevich, O.Kalinkevich, A.Pisarek, M.Simka, W.Погорєлов, Максим ВолодимировичПогорелов, Максим ВладимировичPohorielov, Maksym Volodymyrovych2021-03-252021-03-252020Korniienko V, Oleshko O, Husak Y, Deineka V, Holubnycha V, Mishchenko O, Kazek-Kęsik A, Jakóbik-Kolon A, Pshenychnyi R, Leśniak-Ziółkowska K, Kalinkevich O, Kalinkevich A, Pisarek M, Simka W, Pogorielov M. Formation of a Bacteriostatic Surface on ZrNb Alloy via Anodization in a Solution Containing Cu Nanoparticles. Materials. 2020; 13(18):3913. https://doi.org/10.3390/ma131839130000-0002-1241-25500000-0002-2217-37170000-0003-2439-32430000-0002-2560-93790000-0001-9372-7791https://essuir.sumdu.edu.ua/handle/123456789/82869High strength, excellent corrosion resistance, high biocompatibility, osseointegration ability, and low bacteria adhesion are critical properties of metal implants. Additionally, the implant surface plays a critical role as the cell and bacteria host, and the development of a simultaneously antibacterial and biocompatible implant is still a crucial challenge. Copper nanoparticles (CuNPs) could be a promising alternative to silver in antibacterial surface engineering due to low cell toxicity. In our study, we assessed the biocompatibility and antibacterial properties of a PEO (plasma electrolytic oxidation) coating incorporated with CuNPs (Cu nanoparticles). The structural and chemical parameters of the CuNP and PEO coating were studied with TEM/SEM (Transmission Electron Microscopy/Scanning Electron Microscopy), EDX (Energy-Dispersive X-ray Dpectroscopy), and XRD (X-ray Diffraction) methods. Cell toxicity and bacteria adhesion tests were used to prove the surface safety and antibacterial properties. We can conclude that PEO on a ZrNb alloy in Ca–P solution with CuNPs formed a stable ceramic layer incorporated with Cu nanoparticles. The new surface provided better osteoblast adhesion in all time-points compared with the nontreated metal and showed medium grade antibacterial activities. PEO at 450 V provided better antibacterial properties that are recommended for further investigation.enCC BY 4.0plasma electrolytic oxidationdental implantzirconium-niobium alloybiocompatibilitybacterial adhesionArticle