Please use this identifier to cite or link to this item: http://essuir.sumdu.edu.ua/handle/123456789/48362
Title: Analysis of association Lys198Asn polymorphism of EDN1 gene with risk factors of ischemic atherothrombotic stroke in the Ukrainian population
Authors: Oleshko, Tetiana Bohdanivna
Svyrydenko, Diana Yuriivna
Yurchenko, Viktoriia Serhiivna
Obukhova, Olha Anatoliivna 
Harbuzova, Viktoriia Yuriivna 
Keywords: інсульти
инсульты
strokes
Issue Year: 2016
Citation: Analysis of association Lys198Asn polymorphism of EDN1 gene with risk factors of ischemic atherothrombotic stroke in the Ukrainian population / T.B. Oleshko, D.Y. Svyrydenko, V.S. Yurchenko [et al.] // IV Eurasian congress of cardiologists. Yerevan, Armenia, 10-11 October 2016. – P. 46.
Abstract: One of the most important medical and social problems are acute cerebrovascular disorders, among which the most part is ischemic stroke. Known that in the development of stroke leading role belongs to endothelial dysfunction (ED), the main manifestation of which is the metabolic changes of the vascular wall, the release of a significant amount endothelin-1 (EDN1) and the development of vasoconstriction. Therefore, one of the candidate genes, polymorphisms that can be associated with a predisposition to the development of ED and consequently contribute to stroke, is EDN1 gene. In order to improve the prevention of stroke, we decided carry out a study among healthy persons and identify possible susceptibility. The aim of our study was to analyze the association Lys198Asn polymorphism of EDN1 gene with ischemic atherothrombotic stroke (IAS) risk factors in the Ukrainian population.
URI: http://essuir.sumdu.edu.ua/handle/123456789/48362
Type: Theses
Appears in Collections:Наукові видання (МІ)

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