The features of morphological changes in the urinary bladder under combined effect of heavy metal salts

Romaniuk, Anatolii Mykolaiovych; Sikora, Vladyslav Volodymyrovych; Lyndin, Mykola Serhiiovych; Smiianov, Vladyslav Anatoliiovych; Sikora, Volodymyr Vitaliiovych; Lyndina, Yuliia Mykolaivna; Piddubnyi, Artem Mykhailovych; Hyriavenko, Nataliia Ivanivna; Korobchanska, Anna Borysivna

Please use this identifier to cite or link to this item: http://essuir.sumdu.edu.ua/handle/123456789/74944

Or use following links to share this resource in social networks: Recommend this item

Title	The features of morphological changes in the urinary bladder under combined effect of heavy metal salts
Authors	Romaniuk, Anatolii Mykolaiovych Sikora, Vladyslav Volodymyrovych Lyndin, Mykola Serhiiovych Smiianov, Vladyslav Anatoliiovych Sikora, Volodymyr Vitaliiovych Lyndina, Yuliia Mykolaivna Piddubnyi, Artem Mykhailovych Hyriavenko, Nataliia Ivanivna Korobchanska, Anna Borysivna
ORCID	http://orcid.org/0000-0003-2560-1382 http://orcid.org/0000-0002-4147-6879 http://orcid.org/0000-0003-4385-3903 http://orcid.org/0000-0001-8164-9706 http://orcid.org/0000-0003-4021-2334 http://orcid.org/0000-0002-2132-0965 http://orcid.org/0000-0002-6508-0131 http://orcid.org/0000-0002-9805-014X
Keywords	солі важких металів соли тяжелых металлов heavy metal salts сечовий міхур мочевой пузырь urinary bladder гістологічні дослідження гистологические исследования histological studies імуногістохімічні дослідження иммуногистохимические исследования immunohistochemical studies Ki-67 Hps90α зовнішнє середовище окружающая среда environment
Type	Article
Date of Issue	2017
URI	http://essuir.sumdu.edu.ua/handle/123456789/74944
Publisher	Interventional Medicine & Applied Science
License
Citation	The features of morphological changes in the urinary bladder under combined effect of heavy metal salts / A. Romaniuk, V. Sikora, M. Lyndin et al. // Interventional Medicine & Applied Science. - 2017. - № 9(2). - P. 1-7. DOI:10.1556/1646.9.2017.2.09.
Abstract	Abstract: Purpose: This study is aimed to the investigation of the features of morphological changes in the urinary bladder of mature rats. Results: Received results shown that the experimental group of rats that had the intake of heavy metal salts (HMS) mixture during 30 and 90 days were observed histological and immunohistochemical changes in all structures of the urinary bladder. Depending on the period of influence of heavy metal ions on the wall of the organ, the pathological changes developed in cellular layers of the wall can lead to degenerative and later to atrophic and sclerotic changes. Conclusions: This study demonstrates that high concentrations ofHMS can significantly influence the body. The histological and immunohistochemical studies showed that the influence of the HMS combination leads to deep morphological changes in all structures of the urinary bladder. These changes depend on the period of intake of HMS. Analysis of the obtained results demonstrates the dependence of expression of morphological changes in the urinary bladder on the experiment duration. The final result of these changes may lead to the disorders of bladder’s functions.
Appears in Collections:	Наукові видання (НН МІ)