Видання зареєстровані авторами шляхом самоархівування
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Item Improvement of Skeletal Muscle Regeneration by Platelet-Rich Plasma in Rats with Experimental Chronic Hyperglycemia(Hindawi, 2020) Raed, Rtail; Максимова, Олена Сергіївна; Максимова, Елена Сергеевна; Maksymova, Olena Serhiivna; Ілляшенко, Вячеслав Юрійович; Ильяшенко, Вячеслав Юрьевич; Illiashenko, Viacheslav Yuriiovych; Гортинська, Олена Миколаївна; Гортинская, Елена Николаевна; Hortynska, Olena Mykolaivna; Кореньков, Олексій Володимирович; Кореньков, Алексей Владимирович; Korenkov, Oleksii Volodymyrovych; Москаленко, Павло Олександрович; Москаленко, Павел Александрович; Moskalenko, Pavlo Oleksandrovych; Mohamad, Nasser; Ткач, Геннадій Федорович; Ткач, Геннадий Федорович; Tkach, Hennadii FedorovychHerein, the structural effect of autologous platelet-rich plasma (PRP) on posttraumatic skeletal muscle regeneration in rats with chronic hyperglycemia (CH) was tested. 130 white laboratory male rats divided into four groups (I—control; II—rats with CH; III—rats with CH and PRP treatment; and IV—rats for CH confirmation) were used for the experiment. CH was simulated by streptozotocin and nicotinic acid administration. Triceps surae muscle injury was reproduced by transverse linear incision. Autologous PRP was used in order to correct the possible negative CH effect on skeletal muscle recovery. On the 28th day after the injury, the regenerating muscle fiber and blood vessel number in the CH+PRP group were higher than those in the CH rats. However, the connective tissue area in the CH group was larger than that in the CH+PRP animals. The amount of agranulocytes in the regenerating muscle of the CH rats was lower compared to that of the CH+PRP group. The histological analysis of skeletal muscle recovery in CH+PRP animals revealed more intensive neoangiogenesis compared to that in the CH group. Herewith, the massive connective tissue development and inflammation signs were observed within the skeletal muscle of CH rats. Obtained results suggest that streptozotocin-induced CH has a negative effect on posttraumatic skeletal muscle regeneration, contributing to massive connective tissue development. The autologous PRP injection promotes muscle recovery process in rats with CH, shifting it away from fibrosis toward the complete muscular organ repair.Item Application of saliva crystalloscopy methods in the diagnosis of malignant tumours of salivary glands and Sjögren disease(International Academy of Science and Higher Education, 2016) Москаленко, Павло Олександрович; Москаленко, Павел Александрович; Moskalenko, Pavlo Oleksandrovych; Лахтін, Юрій Володимирович; Лахтин, Юрий Владимирович; Lakhtin, Yurii Volodymyrovych; Levkov, A.A.; Сміянов, Юрій Владиславович; Смиянов, Юрий Владиславович; Smiianov, Yurii VladyslavovychA high informational content of saliva crystalloscopy in the diagnosis of salivary glands tumours was proven; typical symptoms of Sjögren disease and malignant tumours of the salivary glands were found on the ground of the analysis of the presented research method.