Mesoporous Silica and Composite Nanostructures for Theranostics

Khanadeev, V.A.; Khlebtsov, B.N.; Terentyuk, G.S.; Chumakov, D.S.; Basko, M.V.; Bucharskaya, A.B.; Genina, E.A.; Bashkatov, A.N.; Khlebtsov, N.G.

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Title	Mesoporous Silica and Composite Nanostructures for Theranostics
Authors	Khanadeev, V.A. Khlebtsov, B.N. Terentyuk, G.S. Chumakov, D.S. Basko, M.V. Bucharskaya, A.B. Genina, E.A. Bashkatov, A.N. Khlebtsov, N.G.
ORCID
Keywords	Mesoporous silica Nanoparticles Nanocomposites Theranostics Photodynamic therapy
Type	Conference Papers
Date of Issue	2013
URI	http://essuir.sumdu.edu.ua/handle/123456789/35481
Publisher	Sumy State University
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Citation	Mesoporous Silica and Composite Nanostructures for Theranostics [Текст] / V.A. Khanadeev, B.N. Khlebtsov, G.S. Terentyuk et al. // Nanomaterials: Applications & Properties (NAP-2013) : 3-nd International conference, Alushta, the Crimea, September 16-21, 2013 / Edited by: A. Pogrebnjak. - Sumy : Sumy State University, 2013. - V.2, No4. - 04NABM25
Abstract	We discus methods for fabrication of silica and composite nanoparticles, which can be used in various biomedical applications. The most promising types of such nanostructures are hollow silica nanosheres, sil-ica coated plasmon-resonant nanoparticles (gold nanorods and gold-silver nanocages) and nanorattles. Mesoporous silica shell can be doped by desirable targeting molecules. Here we present the results of for-mation of nanocomposites composed of gold nanorods and double-layer silica shell. The secondary mesopo-rous silica shell is doped with a photosensitizer (hematoporphyrine in our case). We demonstate some of promising theranostics applications of these nanocomposites for bioimaging and in vivo therapy of tumors. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/35481
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