Please use this identifier to cite or link to this item: http://essuir.sumdu.edu.ua/handle/123456789/37238
Title: Development and Investigation of Emulsion Form for Antiepileptic Drug Carbamazepine
Authors: Prokhorov, D.I.
Antyasova, M.N.
Groza, N.V.
Kapitza, I.G.
Keywords: Carbamazepine
Nanoemulsion
Anticonvulsant activity
Epilepsy
Parenteral formulation
Drug solubilization
Issue Year: 2014
Publisher: Sumy State University
Citation: Proc. NAP 3, 02NABM02 (2014)
Abstract: This study was directed to obtain a carbamazepine nanoemulsion for intravenous administration which consists of medium-chain trigycerides (Myritol) used as oil phase and Tween 80 as emulsifier. The spontaneous emulsification method with additional sonication was used to prepare different formulation containing 0.5 mg/ml carbamazepine. The nanoemulsions were evaluated concerning droplet size, zeta potential and drug content. Preliminary studies of anticonvulsant activity for resulting formulation were carried out.
URI: http://essuir.sumdu.edu.ua/handle/123456789/37238
Type: Article
Appears in Collections:Наукові видання (ЕлІТ)

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