Fluorescent Glycine-Coated Silver Nanoparticles as Bio-Imaging Agents for the Neural Stem Cells

Kravets, V.V.; Almemar, Z.; Kotko, A.V.; Dmytruk, I.M.; Pinchuk, A.O.

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Title	Fluorescent Glycine-Coated Silver Nanoparticles as Bio-Imaging Agents for the Neural Stem Cells
Authors	Kravets, V.V. Almemar, Z. Kotko, A.V. Dmytruk, I.M. Pinchuk, A.O.
ORCID
Keywords	silver nanoparticles stem cells toxicity bio-imaging surface plasmon resonance photoluminescence
Type	Conference Papers
Date of Issue	2015
URI	http://essuir.sumdu.edu.ua/handle/123456789/42509
Publisher	Sumy State University
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Citation	Fluorescent Glycine-Coated Silver Nanoparticles as Bio-Imaging Agents for the Neural Stem Cells [Текст] / A.O. Pinchuk, V.V. Kravets, Z. Almemar et al. // Nanomaterials: Applications & Properties (NAP-2015) : Proceedings of the International Conference. — Sumy : Sumy State University, 2015. — V.4, No2. — 02NABM02.
Abstract	We study experimentally the photoluminescence of small glycine-coated silver nanoparticles and their application as the bio-imaging markers of the neural stem cells. In addition we study nanoparticle’s toxic effects on the neural stem cells. Glycine-coated silver nanoparticles were synthesized using a thermal reduction of silver nitrate in a glycine matrix and size-separated via centrifugation. The properties of the nanoparticles were characterized using transmission electron microscopy, extinction and photoluminescence spectroscopy. Our results indicate that the nanoparticles have deleterious effects on the cells and showed an amplified increase in their death rates. In fixed cells the particles penetrate the membranes within an hour and 25 minutes of incubation, but do not penetrate into the body of the cell.
Appears in Collections:	Наукові видання (ЕлІТ)