Навчально-науковий медичний інститут (НН МІ)

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    Morphological and crystal chemical characteristic of panсreatic lithiasis
    (Aluna Publishing, 2018) Кравець, Олександр Валерійович; Кравец, Александр Валерьевич; Kravets, Oleksandr Valeriiovych; Даниленко, Ігор Анатолійович; Даниленко, Игорь Анатольевич; Danylenko, Ihor Anatoliiovych; Смородська, Ольга Миколаївна; Смородская, Ольга Николаевна; Smorodska, Olha Mykolaivna; Піддубний, Артем Михайлович; Поддубный, Артем Михайлович; Piddubnyi, Artem Mykhailovych; Закорко, Інна-Маргарита Сергіївна; Закорко, Инна-Маргарита Сергеевна; Zakorko, Inna-Marharyta Serhiivna; Данильченко, Сергій Миколайович; Данильченко, Сергей Николаевич; Danylchenko, Serhii Mykolaiovych; Москаленко, Роман Андрійович; Москаленко, Роман Андреевич; Moskalenko, Roman Andriiovych; Кононенко, Микола Григорович; Кононенко, Николай Григорьевич; Kononenko, Mykola Hryhorovych; Романюк, Анатолій Миколайович; Романюк, Анатолий Николаевич; Romaniuk, Anatolii Mykolaiovych
    Morphological and crystal-chemical study of five cases of pathological biomineralization in the pancreas were conducted in the work. Two stones were located in the pancreatic duct, in other cases - in the ductal system of pancreas. Concretion sizes ranged from 0.5 to 1.5 cm in diameter. Pancreatic lithiasis’ form depended on the location: in the duct of Wirsung single concretions were found (they were relatively large, oval stones with smooth, regular edges); multiple, small concretions with irregular edges, coral-like stones dominated in the ductal system of pancreas. Histological study of pancreas showed the signs of chronic pancreatitis, tissue fibrosis, atrophy and edema of glandular component, system distension of ducts, nidal mix-cell inflammatory infiltrates, vessels’ plethora. Structural phase and chemical analysis of pathological biominerals responded calcite in all studied cases. Conclusion. The presence of pancreatic lithiasis was found to be accompanied by significant morphological changes of the pancreas. The pancreatolith crystal phase was established to be calcium carbonate in the form of calcite.