Навчально-науковий медичний інститут (НН МІ)
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Item Healthcare-associated tubo-ovarian infections in Ukraine: results of a multicenter study (2020-2022)(Aluna Publishing, 2022) Salmanov, A.G.; Терехов, Володимир Андрійович; Терехов, Владимир Андреевич; Terekhov, Volodymyr Andriiovych; Voloshynovych, N.S.; Hrynchuk, O.B.; Ishchak, O.M.; Rud, V.O.; Kolesnik, A.V.To determine the current prevalence of healthcare-associated tubo-ovarian infections in female and antimicrobial resistance of the responsible pathogens in Ukraine.Item Surgical site infection after laparoscopic hysterectomy for benign gynecological disease in Ukraine(Aluna Publishing, 2022) Salmanov, A.G.; Vitiuk, A.D.; Kovalyshyn, O.A.; Терехов, Володимир Андрійович; Терехов, Владимир Андреевич; Terekhov, Volodymyr Andriiovych; Patey, P.M.; Kutytska, T.V.; Voloshynovych, N.S.Objective: The aim: To obtain the first estimates of the current incidence, and risk factors for Surgical Site Infection (SSI) after laparoscopic hysterectomy, and antimicrobial resistance of responsible pathogens in Ukraine. Patients and methods: Materials and methods: We performed a multicenter prospective cohort study was patient-based on surveillance data for SSIs were according to CDC/NHSN methodology. This study included women's undergoing a laparoscopic hysterectomy in 8 hospitals from different regions of Ukraine from January 2018 to December 2020. Results: Results: A total of 1184 women underwent a laparoscopic hysterectomy and 14.9% SSI were identified within 30 days of the operation. Majority of SSI were deep/organ-space. The deep/organ-space SSI incidence rate was 9.2% in total laparoscopic hysterectomy, 15.2% in laparoscopic-assisted vaginal hysterectomy, and 17% in laparoscopic supracervical hysterectomy. The predominant SSI types were Pelvic abscess or cellulitis (19.1%), Salpingitis (16%), Oophoritis (15.3%), Adnexa utery (14.5%), Vaginal cuff infections (13.7%), Endometritis (11.1%), and Chorioamnionitis (9.9%). 93.8% of SSIs were detected post discharge. The most commonly identified pathogen were Escherichia coli (21.6%), Enterobacter spp. (13.1%), followed by Klebsiella spp. (8,1%), Streptococcus spp. (7%), and Pseudomonas aeruginosa (7%). The overall proportion of extended spectrum beta-lactamase production (ESBL) among Enterobacteriaceae was 17.1% and of methicillin-resistance in S. aureus (MRSA)15.8%. Resistance to third-generation cephalosporins was observed in 13.7% E.coli and 8.5% Klebsiella spp. isolates. Carbapenem resistance was in 9.7% of P.aeruginosa strains. Conclusion: Conclusions: Our study identified high incidence rates of SSI within 30 days surveillance of the laparoscopic hysterectomy in Ukraine, and many cases were caused by pathogens that are resistant to antibiotics.