Вплив гуморальних факторів гомеостазу на характер ремоделювання міокарда при хронічній серцевій недостатності

Abstract

The aim of research was the study a humeral factors effect on character myocardium remodeling at chronic heart failure and allocation of attributes - indicators for each type remodeling. It has been found, that the basic humeral factors influencing formation of this or that type remodeling LVH are increase of endocellular Са++, TNF-, aldosterone, norepinephrine, -glutamyltransferasa, EТ-1, the diene conjugate, bilirubin, alkaline phosphates levels and decrease of HDL and the total cholesterol levels. It is revealed, that eccentric type LVH more adverse in comparison with concentric type. A key element of functional system hemodynamics at concentric LVH is the hypertrophy of a myocardium, at eccentric type - index EDD. It is established, that if at eccentric type LVH is marked a RAAS hyperactivation at concentric of LVH its function the exhaustion. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/10842