Please use this identifier to cite or link to this item: http://essuir.sumdu.edu.ua/handle/123456789/37893
Title: Chemical composistion changes of immature rats testis under increased receipts of heavy metals salts
Authors: Moskalenko, Yuliia Vasylivna 
Rieznik, Andrii Vasylovych
Рєзнік, Марія Андріївна
Резник, Мария Андреевна
Rieznik, Mariia Andriyivna
Moskalenko, Roman Andriiovych 
Keywords: сім'яники
семенники
testes
статевонезрілі щури
половонезрелые крысы
immature rats
важкі метали
тяжелые металлы
heavy metals
Issue Year: 2014
Publisher: Pavol Jozef Šafбrik University in Košice, Faculty of Medicine
Citation: Chemical composistion changes of immature rats testis under increased receipts ofheavy metals salts [Text] / Y.V. Moskalenko, A.V. Rieznik, M.A. Rieznik, R.A. Moskalenko // Folia medica Cassoviensia. – 2014. – Tomus 69, No.1, Suppl. 1. – P. 130.
Abstract: Introduction: One reason for the prevalence of infertility in men is high sensitivity of the male reproductive system to adverse exogenous and endogenous factors in the prenatal and early postnatal periods. One of the most common and dangerous pollutants for the reproductive system is the heavy metals compounds (HMC), which have both direct and indirect effects on the development of reproductive system. Aim: To investigate the intensity of accumulation of zinc, copper, lead, manganese, chromium and iron in tissues and structures of immature rat testes under their alimentary intake and under conditions of L-carnitine correction. Material and Methods: The survey was conducted on 128 white lab immature male rats.The tissue of testes was studied by methods of histology, scanning electron microscopy, atomic absorption spectroscopy (AAS) Results: Using spectrophotometry in atomic absorption mode, it is found out that the level of zinc is reduced, and the content of other analyzed trace elements increases. Accumulation of copper, iron, manganese, chromium and lead in testes tissue is mostly expressed in the period of 60 days; iron, lead and chromium show the largest organ tropism. The low rate of HMC accumulation in the testes of rats of breast and suckling age period is explained by the limited intake of xenobiotics via maternal milk. Loss of zinc by testis tissue is caused by antagonistic interactions between chemical elements that come into the body of rats in excessive quantities. Interaction of chemical elements at different levels can lead to secondary violations of chemical and structural homeostasis of the organ, causing further inhibition of its function. Conclusion: The results of chemical analysis of immature animals’ testes, obtained by SEM, indicate the dependence of accumulation of microelements of heavy metals from the morphofunctional activity of the histological structure of the studied organ. Heavy metals mainly accumulate in a functionally active spermatogenic epithelium.
URI: http://essuir.sumdu.edu.ua/handle/123456789/37893
Type: Article
Appears in Collections:Наукові видання (МІ)

Views
Other102
Canada1
Czech Republic3
Germany6
France1
United Kingdom2
Ukraine1
Downloads
Other56
China42
Germany2
France2
Russia1
Ukraine1
United States1


Files in This Item:
File Description SizeFormatDownloads 
Moskalenko_Yu_V.pdf77.86 kBAdobe PDF105Download


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.