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Title Osteopontin overexpression in papillary thyroid carcinoma with mineralization
Authors Moskalenko, Roman Andriiovych  
Romaniuk, Anatolii Mykolaiovych  
Rieznik, Andrii Vasylovych
Lyndin, Mykola Serhiiovych  
Сауляк, Сергій Володимирович
Сауляк, Сергей Владимирович
Sauliak, Serhii Volodymyrovych
Keywords папілярний рак щитоподібної залози
папиллярный рак щитовидной железы
papillary thyroid carcinoma
біомінералізація
биоминерализация
biomineralization
остеопонтин
остеопонтин
odteopontin
Type Conference Papers
Date of Issue 2016
URI http://essuir.sumdu.edu.ua/handle/123456789/46494
Publisher Springer
License
Citation Moskalenko, R. Osteopontin overexpression in papillary thyroid carcinoma with biomineralization / R. Moskalenko, A. Romaniuk, A. Rieznik [et al.] // Virchows Arch. – 2016. – Vol. 469, Suppl. 1. – S.74.
Abstract Objective: Pathological mineralization (ectopic calcification) is an often finding in papillary thyroid carcinoma (PTC). The concept of pathological mineralization in papillary thyroid carcinoma included psammoma’s bodies, bone formation, stromal and vascular calcification. Osteopontin (OPN) is a glyco-phosphoprotein that is expressed and secreted by numerous human cancers. Osteopontin is upregulated at sites of pathologic, ectopic calcification—presumably at least in part to inhibit debilitating mineralization in these soft tissues. We investigated the expression of OPN and her correlation with pathological mineralization in PTC.
Appears in Collections: Наукові видання (МІ)

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