Please use this identifier to cite or link to this item: http://essuir.sumdu.edu.ua/handle/123456789/46494
Title: Osteopontin overexpression in papillary thyroid carcinoma with mineralization
Authors: Moskalenko, Roman Andriiovych 
Romaniuk, Anatolii Mykolaiovych 
Rieznik, Andrii Vasylovych
Lyndin, Mykola Serhiiovych 
Сауляк, Сергій Володимирович
Сауляк, Сергей Владимирович
Sauliak, Serhii Volodymyrovych
Keywords: папілярний рак щитоподібної залози
папиллярный рак щитовидной железы
papillary thyroid carcinoma
біомінералізація
биоминерализация
biomineralization
остеопонтин
остеопонтин
odteopontin
Issue Year: 2016
Publisher: Springer
Citation: Moskalenko, R. Osteopontin overexpression in papillary thyroid carcinoma with biomineralization / R. Moskalenko, A. Romaniuk, A. Rieznik [et al.] // Virchows Arch. – 2016. – Vol. 469, Suppl. 1. – S.74.
Abstract: Objective: Pathological mineralization (ectopic calcification) is an often finding in papillary thyroid carcinoma (PTC). The concept of pathological mineralization in papillary thyroid carcinoma included psammoma’s bodies, bone formation, stromal and vascular calcification. Osteopontin (OPN) is a glyco-phosphoprotein that is expressed and secreted by numerous human cancers. Osteopontin is upregulated at sites of pathologic, ectopic calcification—presumably at least in part to inhibit debilitating mineralization in these soft tissues. We investigated the expression of OPN and her correlation with pathological mineralization in PTC.
URI: http://essuir.sumdu.edu.ua/handle/123456789/46494
Type: Theses
Appears in Collections:Наукові видання (МІ)

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