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Title: The case of undiagnosed immunodeficiency in child from mother with leukemia anamnesis
Authors: Smiian, Oleksandr Ivanovych 
Lyndin, Mykola Serhiiovych 
Romaniuk, Oksana Kostiantynivna
Sikora, Vladyslav Volodymyrovych 
Piddubnyi, Artem Mykhailovych 
Yurchenko, Alla Vladyslavivna
Korobchanska, Anna Borysivna
Tarasova, Iryna Vitaliivna
Hyriavenko, Nataliia Ivanivna 
Сікора, Катерина
Сикора, Екатерина
Sikora, Kateryna
Romaniuk, Anatolii Mykolaiovych 
Keywords: гострий лімфобластний лейкоз
острый лимфобластный лейкоз
acute lymphoblastic leukemia
імунна система
иммунная система
immune system
Issue Year: 2018
Publisher: Interventional Medicine & Applied Science
Citation: The case of undiagnosed immunodeficiency in child from mother with leukemia anamnesis / O. Smiyan, M. Lyndin, O. Romaniuk et al. // Interventional Medicine and Applied Science. - 2018. - Vol.10(4). - P. 216-221. DOI: 10.1556/1646.10.2018.46
Abstract: Acute lymphoblastic leukemia (ALL) in pregnant women is rare experience, but it can complicate the gestation by increasing the risk of miscarriage and premature birth. However, the adequate carrying of the pregnancy is possible for women who suffered from leukemia in childhood and achieved the remission during the treatment. Furthermore, there are some facts about the possibility of immunosuppression in children whose parents suffer from various immunodeficiency disorders, including ALL. This clinical case demonstrates the importance of correct diagnostics in order to reveal the congenital pathologies of the immune system in children, whose parents suffered from lymphocytic leukemia, even in case of full clinical and laboratory remission for a significant period of time. In the hospital, the thread metric approach was used for sepsis diagnostics. Conducted treatment was ineffective due to the inadequate immune response in the child and lack of the targeted adjusted measures to immunodeficiency disorder. The present case demonstrates the congenital T-cells immunodeficiency in a child who was complicated by the development of acute ulceronecrotic enterocolitis after vaccination. The treatment that was targeted mainly at the agent eradication did not give the desired results due to non-responsiveness of the immune system of the child.
Type: Article
Appears in Collections:Наукові видання (МІ)

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