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Title The case of undiagnosed immunodeficiency in child from mother with leukemia anamnesis
Authors Smiian, Oleksandr Ivanovych  
Lyndin, Mykola Serhiiovych  
Romaniuk, Oksana Kostiantynivna
Sikora, Vladyslav Volodymyrovych  
Piddubnyi, Artem Mykhailovych  
Yurchenko, Alla Vladyslavivna
Korobchanska, Anna Borysivna
Tarasova, Iryna Vitaliivna
Hyriavenko, Nataliia Ivanivna  
Sikora, Kateryna Oleksiivna
Romaniuk, Anatolii Mykolaiovych  
Keywords гострий лімфобластний лейкоз
острый лимфобластный лейкоз
acute lymphoblastic leukemia
імунодефіцит
иммунодефицит
immunodeficiency
вакцинація
вакцинация
vaccination
імунна система
иммунная система
immune system
селезінка
селезенка
spleen
тимус
тимус
thymus
Type Article
Date of Issue 2018
URI http://essuir.sumdu.edu.ua/handle/123456789/74947
Publisher Interventional Medicine & Applied Science
License
Citation The case of undiagnosed immunodeficiency in child from mother with leukemia anamnesis / O. Smiyan, M. Lyndin, O. Romaniuk et al. // Interventional Medicine and Applied Science. - 2018. - Vol.10(4). - P. 216-221. DOI: 10.1556/1646.10.2018.46
Abstract Acute lymphoblastic leukemia (ALL) in pregnant women is rare experience, but it can complicate the gestation by increasing the risk of miscarriage and premature birth. However, the adequate carrying of the pregnancy is possible for women who suffered from leukemia in childhood and achieved the remission during the treatment. Furthermore, there are some facts about the possibility of immunosuppression in children whose parents suffer from various immunodeficiency disorders, including ALL. This clinical case demonstrates the importance of correct diagnostics in order to reveal the congenital pathologies of the immune system in children, whose parents suffered from lymphocytic leukemia, even in case of full clinical and laboratory remission for a significant period of time. In the hospital, the thread metric approach was used for sepsis diagnostics. Conducted treatment was ineffective due to the inadequate immune response in the child and lack of the targeted adjusted measures to immunodeficiency disorder. The present case demonstrates the congenital T-cells immunodeficiency in a child who was complicated by the development of acute ulceronecrotic enterocolitis after vaccination. The treatment that was targeted mainly at the agent eradication did not give the desired results due to non-responsiveness of the immune system of the child.
Appears in Collections: Наукові видання (МІ)

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