Please use this identifier to cite or link to this item: http://essuir.sumdu.edu.ua/handle/123456789/75464
Or use following links to share this resource in social networks: Recommend this item
Title Optimization of the treatment of rotavirus infection in children by using bacillus clausii
Authors Smiian, Oleksandr Ivanovych  
Smiian, Kateryna Oleksandrivna  
Bynda, Tetiana Parfeniivna  
Loboda, Andrii Mykolaiovych  
Popov, Serhii Vitaliiovych  
Vysotskyi, Ihor Yuriiovych  
Moshchych, O.P.
Vasylieva, Olena Hennadiivna  
Manko, Yuliia Anatoliivna  
Ovsianko, Olena Leonidivna  
Kolesnikova, Mariia Viktorivna  
Dolgova, Nataliia Oleksandrivna  
Aleksakhina, Tetiana Oleksiivna  
Al-Rawashdeh, Bara
ORCID http://orcid.org/0000-0001-8225-0975
http://orcid.org/0000-0002-8030-6418
http://orcid.org/0000-0001-6020-6463
http://orcid.org/0000-0002-5400-773X
http://orcid.org/0000-0002-1789-1474
http://orcid.org/0000-0002-6357-3362
http://orcid.org/0000-0003-4470-8740
http://orcid.org/0000-0003-3348-2862
http://orcid.org/0000-0002-0334-4891
http://orcid.org/0000-0003-3060-158X
http://orcid.org/0000-0002-5091-4762
http://orcid.org/0000-0002-9905-330X
Keywords ротавірус
rotavirus
гуморальний імунітет
гуморальный иммунитет
humoral immunity
діти
дети
children
IgA
sIgA
IgM
IgG
Type Article
Date of Issue 2019
URI http://essuir.sumdu.edu.ua/handle/123456789/75464
Publisher Aluna Publishing
License
Citation Optimization of the treatment of rotavirus infection in children by using bacillus clausii / O.I. Smiian, K.O. Smiian-Horbunova, T.P. Bynda et al. // Wiadomosci Lekarskie. - 2019. - T. 72, №7. - P. 1320-1323.
Abstract Rotavirus infection is a leading place in the structure of acute intestinal infections in children. Rotavirus is excreted in 4 0-60 % of children hospitalized with gastroenteritis all over the world. Every year, 2 million patients are hospitalized with a severe form of RVI, 25 million need medical help from a doctor and 111 million cases are treated at home. The purpose of our study was to optimize the treatment of rotavirus infection in children by using Bacillus clausii. There were 65 children with a rotavirus infection under supervision. The control group was consisted of 28 practically healthy children. The study of humoral immunity was carried out on the basis of determining the serum content of immunoglobulin G, immunoglobulin M, immunoglobulin A, and secretory immunoglobulin A in coprofiltrate. In the process of treatment, the children were divided into two groups: the first received standard treatment, the second group were added to standard treatment with a probiotic drug (Bacillus clausii). In children with RVI with modified treatment main symptoms were reduced compared with the children receiving standard treatment, (p <0.001). In patients with rotavirus infection in the acute period of the disease, a decrease in the concentration of IgA (p < 0.001) and an increase in IgM (p < 0.001) in serum and a decrease in sIgA (p < 0.001) in coprofiltrate was observed in comparison with children in control group. In the period of reconvalescence in children after the traditional treatment, it wasn't revealed normalization of the immunoglobulins. Patients receiving a probiotic drug in addition to traditional treatment it was revealed normalization of the parameters of serum immunoglobulins A, M, G and sIgA in coprofiltrate. So, the probiotic drug containing Bacillus clausii has a positive effect on the humoral immune system in children with rotavirus infection.
Appears in Collections: Наукові видання (НН МІ)

Views

Armenia Armenia
1
Australia Australia
-173057546
Austria Austria
1
Bangladesh Bangladesh
-284775810
Belgium Belgium
895123196
Brazil Brazil
-1990917964
Canada Canada
1
China China
-574005780
Colombia Colombia
1
Croatia Croatia
1
Cuba Cuba
548099409
Czechia Czechia
1
Côte d’Ivoire Côte d’Ivoire
1
Ecuador Ecuador
1
Egypt Egypt
1091739344
Ethiopia Ethiopia
1
France France
1317020864
Germany Germany
1091739345
Ghana Ghana
1
Greece Greece
1
Hong Kong SAR China Hong Kong SAR China
-1314531128
Hungary Hungary
6944855
India India
83459
Iran Iran
1
Iraq Iraq
1866912208
Ireland Ireland
-844034955
Israel Israel
207585
Japan Japan
1
Jordan Jordan
1
Kazakhstan Kazakhstan
1
Kenya Kenya
1
Lebanon Lebanon
1
Lithuania Lithuania
1866912205
Malaysia Malaysia
-995365664
Mexico Mexico
121638
Mongolia Mongolia
1
Morocco Morocco
1
Netherlands Netherlands
343989031
Pakistan Pakistan
-9423908
Paraguay Paraguay
199340
Peru Peru
175229
Philippines Philippines
102641
Portugal Portugal
1
Saudi Arabia Saudi Arabia
6944859
Senegal Senegal
1859191641
Singapore Singapore
-844034953
South Korea South Korea
152102
Sweden Sweden
6944863
Taiwan Taiwan
1637333890
Thailand Thailand
4204
Turkey Turkey
592983743
Ukraine Ukraine
-574005779
United Arab Emirates United Arab Emirates
1
United Kingdom United Kingdom
22831
United States United States
1091739351
Unknown Country Unknown Country
131090564
Vietnam Vietnam
-173057544

Downloads

Argentina Argentina
1
Bangladesh Bangladesh
1386
Brazil Brazil
185475
China China
1
Colombia Colombia
-2133372078
Czechia Czechia
-944268456
Denmark Denmark
1
Ecuador Ecuador
1
Egypt Egypt
1091739349
Germany Germany
-844034959
Hong Kong SAR China Hong Kong SAR China
1
India India
1091739346
Iran Iran
26
Iraq Iraq
28
Ireland Ireland
1
Italy Italy
1866912206
Lithuania Lithuania
1866912204
Malaysia Malaysia
-995365663
Mexico Mexico
112655
Mozambique Mozambique
1
Pakistan Pakistan
312998952
Paraguay Paraguay
111342
Peru Peru
1
Philippines Philippines
1
Poland Poland
-944268459
Singapore Singapore
1
South Africa South Africa
1
Turkey Turkey
1
Ukraine Ukraine
-1535597316
United Arab Emirates United Arab Emirates
1
United Kingdom United Kingdom
1
United States United States
-844034950
Unknown Country Unknown Country
-1314531126
Uruguay Uruguay
1
Vietnam Vietnam
-844034958

Files

File Size Format Downloads
Smiian_humoral_immunity.pdf 172.44 kB Adobe PDF 126172315

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.