Streptosotzin diabetes model

Abstract

Diabetes mellitus (DM) is a widespread disease leading to the development of serious complications, disability and premature death. A mandatory factor in the pathogenesis of type 1 diabetes is absolute insulin deficiency, leading to characteristic metabolic disorders. The fundamental treatment of Type 1 diabetes costs a lot of millions dollars every year for the past 100 years. Medicine spends a huge amount of money for daily insulin injections. Insulin therapy prevents death of patients from hyperglycemic coma, but doesn’t prevent the development of severe chronic complications. That is why, the search of more effective and preferably cardinal ways for antidiabetic treatment is extremely important. Great attention is paid to experiments on animals with experimental diabetes.