Наукові видання (НН МІ)
Permanent URI for this collectionhttps://devessuir.sumdu.edu.ua/handle/123456789/132
Browse
2 results
Search Results
Item Toluidine blue for the detection of sentinel lymph nodes in patients with thyroid cancer(Termedia Publishing House, 2022) Москаленко, Юлія Василівна; Moskalenko, Yuliia Vasylivna; Курочкін, Андрій Вікторович; Kurochkin, Andrii Viktorovych; Винниченко, Ігор Олександрович; Vynnychenko, Ihor Oleksandrovych; Кравець, Олександр Валерійович; Kravets, Oleksandr Valeriiovych; Піддубний, Артем Михайлович; Piddubnyi, Artem Mykhailovych; Москаленко, Роман Андрійович; Moskalenko, Roman Andriiovych; Потапов, Олександр Олександрович; Potapov, Oleksandr OleksandrovychIntroduction: Thyroid cancer (TC) demonstrates steady growth in incidence worldwide and remains an urgent problem in oncology. The detection of sentinel lymph nodes (SLN) with a selective dye and further histological examination in selecting the proper (personalized) surgical strategy and the volume of surgical intervention for clinically undetermined regional lymph nodes. The purpose of the study is to evaluate the effectiveness and safety of intraoperative detection of SLN with a 1% toluidine blue aqueous solution. Material and methods: The significant tasks are to identify the pattern of TC metastases to cervical lymph nodes, to establish the prevalence of “skip” metastases, to compare the frequency of complications after total thyroidectomy and central neck dissection and lateral neck dissection with total thyroidectomy and central neck dissection, and to determine the feasibility of the application of lateral neck dissections in patients with papillary and follicular TC without metastases to regional lymph nodes (according to physical examination and ultrasound). Results: According to our data the SLN identification rate was 97.6%. Sensitivity, specificity, positive predictive value, negative predictive value, and frequency of false negative and false positive results was 89.2, 94.6, 88.03, 95.16, 10.8, and 5.4%, respectively. The most common metastasis was in the central neck compartment (83.7%). Skip metastases were determined in 4.9% of patients. Conclusions: The low prevalence of “skip” metastases and a significant risk of postoperative complications (wound exudation, lymphorrhagia, inflammation, hypoparathyroidism, paresis of the vocal cords) support the idea that lateral neck dissection is appropriate only in cases of confirmed metastases by physical examination and/or ultrasound at the preoperative stage.Item The program of complex differentiated medical and psychological rehabilitation of suicidal behavior in dementia(Cambridge University Press, 2021) Мудренко, Ірина Григорівна; Мудренко, Ирина Григорьевна; Mudrenko, Iryna Hryhorivna; Потапов, Олександр Олександрович; Потапов, Александр Александрович; Potapov, Oleksandr Oleksandrovych; Alswaeer, E.The course of dementia is accompanied by aggression, wandering, agitation, sexual and eating disorders, suicidal behavior (SB).