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Title Morphological and Crystal Chemical Characteristics of Gallbladder Biomineralization
Authors Moskalenko, Roman Andriiovych  
Danylchenko, Serhii Mykolaiovych
Piddubnyi, Artem Mykhailovych  
Kravets, Oleksandr Valeriiovych  
Chorna, Inna Valentynivna  
Kolomiiets, Olena Olehivna  
Romaniuk, Anatolii Mykolaiovych  
ORCID http://orcid.org/0000-0002-2342-0337
http://orcid.org/0000-0002-6508-0131
http://orcid.org/0000-0003-3394-6671
http://orcid.org/0000-0002-3094-4518
http://orcid.org/0000-0002-6464-4839
http://orcid.org/0000-0003-2560-1382
Keywords холецистит
cholecystitis
рак жовчного міхура
рак желчного пузыря
gallbladder cancer
порцеляновий жовчний міхур
фарфоровый желчный пузырь
porcelain gallbladder
гідроксиапатит
гидроксиаппатит
hydroxyapatite
карбонат кальцію
карбонат кальция
calcium carbonatee
Type Article
Date of Issue 2020
URI https://essuir.sumdu.edu.ua/handle/123456789/79162
Publisher Acta facultatis medicae Naissensis
License Creative Commons Attribution 4.0 International License
Citation Morphological and Crystal Chemical Characteristics of Gallbladder Biomineralization / R.A. Moskalenko, S.M. Danilchenko, A.M. Piddubnyi et al. // Acta facultatis medicae Naissensis. – 2020. – №37. – С. 139–148.
Abstract Pathological biomineralization can be found in some gallbladder (GB) diseases such as chronic calculous cholecystitis (CCCh), gallbladder cancer (GBC) and porcelain gallbladder (PGB). The aim of the work was to analyze the morphology of pathological biomineralization in GB tissue in CCCh, GBC and PGB. Five cases of PGB, 10 samples of CCCh and 5 cases of GBC with biomineralization were selected for this study. All samples were examined by histology, histochemistry and scanning electron microscopy with X-ray diffraction. The X-ray diffraction of mineral deposits of PGB wall and GB concretions revealed their different mineral composition. All PGB and GBC samples had the presence of hydroxyapatite. Calcium-containing GB concretions were composed of calcium carbonate with the presence of trace amounts of other calcium phosphate phases (vaterite, dolomite). We did not find cancer in all PGB cases. The different crystal phases of biominerals were found in the wall (PGB and GBC) and in the GB cavity (CCCh) during pathology development. The difference between mineral content of biominerals can be caused by various conditions and mechanisms of their formation.
Appears in Collections: Наукові видання (НН МІ)

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