Morphological and Crystal Chemical Characteristics of Gallbladder Biomineralization

Moskalenko, Roman Andriiovych; Danylchenko, Serhii Mykolaiovych; Piddubnyi, Artem Mykhailovych; Kravets, Oleksandr Valeriiovych; Chorna, Inna Valentynivna; Kolomiiets, Olena Olehivna; Romaniuk, Anatolii Mykolaiovych

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Title	Morphological and Crystal Chemical Characteristics of Gallbladder Biomineralization
Authors	Moskalenko, Roman Andriiovych Danylchenko, Serhii Mykolaiovych Piddubnyi, Artem Mykhailovych Kravets, Oleksandr Valeriiovych Chorna, Inna Valentynivna Kolomiiets, Olena Olehivna Romaniuk, Anatolii Mykolaiovych
ORCID	http://orcid.org/0000-0002-2342-0337 http://orcid.org/0000-0002-6508-0131 http://orcid.org/0000-0003-3394-6671 http://orcid.org/0000-0002-3094-4518 http://orcid.org/0000-0002-6464-4839 http://orcid.org/0000-0003-2560-1382
Keywords	холецистит cholecystitis рак жовчного міхура рак желчного пузыря gallbladder cancer порцеляновий жовчний міхур фарфоровый желчный пузырь porcelain gallbladder гідроксиапатит гидроксиаппатит hydroxyapatite карбонат кальцію карбонат кальция calcium carbonatee
Type	Article
Date of Issue	2020
URI	https://essuir.sumdu.edu.ua/handle/123456789/79162
Publisher	Acta facultatis medicae Naissensis
License	Creative Commons Attribution 4.0 International License
Citation	Morphological and Crystal Chemical Characteristics of Gallbladder Biomineralization / R.A. Moskalenko, S.M. Danilchenko, A.M. Piddubnyi et al. // Acta facultatis medicae Naissensis. – 2020. – №37. – С. 139–148.
Abstract	Pathological biomineralization can be found in some gallbladder (GB) diseases such as chronic calculous cholecystitis (CCCh), gallbladder cancer (GBC) and porcelain gallbladder (PGB). The aim of the work was to analyze the morphology of pathological biomineralization in GB tissue in CCCh, GBC and PGB. Five cases of PGB, 10 samples of CCCh and 5 cases of GBC with biomineralization were selected for this study. All samples were examined by histology, histochemistry and scanning electron microscopy with X-ray diffraction. The X-ray diffraction of mineral deposits of PGB wall and GB concretions revealed their different mineral composition. All PGB and GBC samples had the presence of hydroxyapatite. Calcium-containing GB concretions were composed of calcium carbonate with the presence of trace amounts of other calcium phosphate phases (vaterite, dolomite). We did not find cancer in all PGB cases. The different crystal phases of biominerals were found in the wall (PGB and GBC) and in the GB cavity (CCCh) during pathology development. The difference between mineral content of biominerals can be caused by various conditions and mechanisms of their formation.
Appears in Collections:	Наукові видання (НН МІ)