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Title Morphofunctional features of articular cartilage structure
Authors Lyndin, Mykola Serhiiovych  
Hlushchenko, Nadiia Volodymyrivna
Sikora, Vladyslav Volodymyrovych  
Lyndina, Yuliia Mykolaivna  
Hyriavenko, Nataliia Ivanivna  
Tkach, Hennadii Fedorovych  
Kurochkina, Viktoriia Semenivna
Romaniuk, Anatolii Mykolaiovych  
Keywords суглобовий хрящ
суставной хращ
articular cartilage
хондроцити
хондроциты
chondrocytes
позаклітинний матрикс
внеклеточный матрикс
extracellular matrix
експресія рецепторів
экспрессия рецепторов
receptors expression
головка стегнової кістки
бедренная головка
femoral head
Type Article
Date of Issue 2019
URI https://essuir.sumdu.edu.ua/handle/123456789/80772
Publisher Branch of the Polish Academy of Sciences in Krakow Jagiellonian University - Collegium Medicum
License In Copyright
Citation Lyndin M, Gluschenko N, Sikora V, Lyndina Yu, Hyryavenko N, Tkach G, Kurochkina V, Romaniuk A. Morphofunctional features of articular cartilage structure. Folia Medica Cracoviensia. 2019;59(3):81-93. DOI: 10.24425/fmc.2019.131138
Abstract Abstract: Background: Articular cartilage is highly-organized nonvascularized tissue which is responsible in humans for pressure absorption under load, as well as for the smoothness of the opposite tangential bone surfaces. The purpose of our research is to study structural and functional features of articular cartilage at light optical level by using state-of-the-art research methods of bone-cartilage tissue. Material and Methods: The study was conducted on samples of femoral heads. Hyperfine sections were subject to hematoxylin and eosin, Van Gieson’s and PAS staining. In order to identify the receptor profile of chondrocytes and the features of protein arrangement in extracellular matrix we undertook an immunohistochemical study. Results: An articular cartilage is quite organized tissue. As any other organ, it has parenchyma and stroma. Parenchyma is represented by one type of cells — chondrocytes, which, depending on how deep they are located in cartilage, have a diff erent shape, size and functional features. The chondrocytes and extracellular matrix have diff erent degrees of receptors expression. Conclusions: The cartilage is being constantly self-renewed, what is manifested by means of a rather slow division of the surface-located chondrocytes and programmed death of dystrophic-modifi ed cells. The features of extracellular matrix structure determine the originality of cell location in different areas of cartilage tissue. Due to synthesis of specific proteins, chondrocytes self-regulate properties of cartilage tissue.
Appears in Collections: Наукові видання (МІ)

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