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Title | Randomized, open-label phase III study of pembrolizumab (pembro) vs docetaxel (doce) in patients (pts) with previously treated NSCLC with PD-L1 tumour proportion score (TPS) ≥1%: KEYNOTE-033 |
Authors |
Zhou, C.
Feng, S. Ma, S. Chen, H. Ma, Z. Huang, C. Zhang, L. He, J. Wang, C. Zhou, J. Danchaivijtr, P. Huang, H-C. Vynnychenko, Ihor Oleksandrovych ![]() Wang, K. Orlandi, F. Sriuranpong, V. Li, B. Ge, J. Dang, T. |
ORCID |
http://orcid.org/0000-0002-2339-6509 |
Keywords |
III study of pembrolizumab docetaxel (doce) |
Type | Conference Papers |
Date of Issue | 2020 |
URI | https://essuir.sumdu.edu.ua/handle/123456789/82104 |
Publisher | Elsevier |
License | Creative Commons Attribution - NonCommercial - NoDerivatives 4.0 International |
Citation | Zhou C., Feng J., Ma S., Chen H., Ma Z., Huang C., Zhang L., He J., Wang C., Zhou J., Danchaivijtr P., Huang H-C., Vynnychenko I.O., Wang K., Orlandi F., Sriuranpong V., Li B., Ge J., Dang T. (2020). Randomized, open-label phase III study of pembrolizumab (pembro) vs docetaxel (doce) in patients (pts) with previously treated NSCLC with PD-L1 tumour proportion score (TPS) ≥1%: KEYNOTE-033. Annals of Oncology. Vol 31, (Suppl 4). S816. Abstract Book of the ESMO Virtual Congress 2020 19 – 21 September / 16 – 18 October 2020. |
Abstract |
In KEYNOTE-010, pembro improved OS vs doce as 2L+ therapy for
advanced NSCLC with PD-L1 TPS 1% and 50%. KEYNOTE-010 did not enroll any pts
from mainland China, which has high NSCLC mortality. KEYNOTE-033 (NCT02864394)
evaluates pembro vs doce in pts with previously treated advanced NSCLC with PD-L1
TPS 1%, with most pts enrolled in mainland China. |
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