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Title Randomized, open-label phase III study of pembrolizumab (pembro) vs docetaxel (doce) in patients (pts) with previously treated NSCLC with PD-L1 tumour proportion score (TPS) ≥1%: KEYNOTE-033
Authors Zhou, C.
Feng, S.
Ma, S.
Chen, H.
Ma, Z.
Huang, C.
Zhang, L.
He, J.
Wang, C.
Zhou, J.
Danchaivijtr, P.
Huang, H-C.
Vynnychenko, Ihor Oleksandrovych  
Wang, K.
Orlandi, F.
Sriuranpong, V.
Li, B.
Ge, J.
Dang, T.
Keywords III study of pembrolizumab
docetaxel (doce)
Type Conference Papers
Date of Issue 2020
URI https://essuir.sumdu.edu.ua/handle/123456789/82104
Publisher Elsevier
License Creative Commons Attribution - NonCommercial - NoDerivatives 4.0 International
Citation Zhou C., Feng J., Ma S., Chen H., Ma Z., Huang C., Zhang L., He J., Wang C., Zhou J., Danchaivijtr P., Huang H-C., Vynnychenko I.O., Wang K., Orlandi F., Sriuranpong V., Li B., Ge J., Dang T. (2020). Randomized, open-label phase III study of pembrolizumab (pembro) vs docetaxel (doce) in patients (pts) with previously treated NSCLC with PD-L1 tumour proportion score (TPS) ≥1%: KEYNOTE-033. Annals of Oncology. Vol 31, (Suppl 4). S816. Abstract Book of the ESMO Virtual Congress 2020 19 – 21 September / 16 – 18 October 2020.
Abstract In KEYNOTE-010, pembro improved OS vs doce as 2L+ therapy for advanced NSCLC with PD-L1 TPS 1% and 50%. KEYNOTE-010 did not enroll any pts from mainland China, which has high NSCLC mortality. KEYNOTE-033 (NCT02864394) evaluates pembro vs doce in pts with previously treated advanced NSCLC with PD-L1 TPS 1%, with most pts enrolled in mainland China.
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