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Title In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium
Authors Oleshko, Oleksandr Mykolaiovych  
Liubchak, Iryna Volodymyrivna
Husak, Yevheniia Volodymyrivna  
Korniienko, Viktoriia Volodymyrivna  
Yusupova, Aziza Farkhodivna
Oleshko, Tetiana Bohdanivna  
Banasiuk, R.
Szkodo, M.
Matros-Taranets, I.
Kazek-Kęsik, A.
Simka, W.
Pohorielov, Maksym Volodymyrovych  
Keywords plasma electrolytic oxidation
titanium
AgNPs
biocompatibility
antibacterial coatings
Type Article
Date of Issue 2020
URI https://essuir.sumdu.edu.ua/handle/123456789/82866
Publisher MDPI
License Creative Commons Attribution 4.0 International License
Citation Oleshko O, Liubchak I, Husak Y, Korniienko V, Yusupova A, Oleshko T, Banasiuk R, Szkodo M, Matros-Taranets I, Kazek-Kęsik A, Simka W, Pogorielov M. In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium. Materials. 2020; 13(19):4359. https://doi.org/10.3390/ma13194359
Abstract Despite the high biocompatibility and clinical effectiveness of Ti-based implants, surface functionalization (with complex osteointegrative/antibacterial strategies) is still required. To enhance the dental implant surface and to provide additional osteoinductive and antibacterial properties, plasma electrolytic oxidation of a pure Ti was performed using a nitrilotriacetic acid (NTA)-based Ag nanoparticles (AgNP)-loaded calcium–phosphate solution. Chemical and structural properties of the surface-modified titanium were assessed using scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) and contact angle measurement. A bacterial adhesion test and cell culture biocompatibility with collagen production were performed to evaluate biological effectiveness of the Ti after the plasma electrolytic process. The NTA-based calcium–phosphate solution with Ag nanoparticles (AgNPs) can provide formation of a thick, porous plasma electrolytic oxidation (PEO) layer enriched in silver oxide. Voltage elevation leads to increased porosity and a hydrophilic nature of the newly formed ceramic coating. The silver-enriched PEO layer exhibits an effective antibacterial effect with high biocompatibility and increased collagen production that could be an effective complex strategy for dental and orthopedic implant development.
Appears in Collections: Наукові видання (МІ)

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