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Title Morphological Peculiarities of Parasitic (Trichosomoides crassicauda) Infection in Rat Urinary Bladder
Authors Sikora, Vladyslav Volodymyrovych  
Lyndin, Mykola Serhiiovych  
Hyriavenko, Nataliia Ivanivna  
Moskalenko, Roman Andriiovych  
Lyndina, Yuliia Mykolaivna  
Sikora, Kateryna Oleksiivna  
Chyzhma, Ruslana Anatoliivna
Diachenko, Olena Olehivna
Romaniuk, Anatolii Mykolaiovych  
ORCID http://orcid.org/0000-0002-4147-6879
http://orcid.org/0000-0003-4385-3903
http://orcid.org/0000-0002-9805-014X
http://orcid.org/0000-0002-2342-0337
http://orcid.org/0000-0002-2132-0965
http://orcid.org/0000-0002-9814-6512
http://orcid.org/0000-0003-2560-1382
Keywords nematode
parasite
rat
Trichosomoides crassicauda
urinary bladder
Type Article
Date of Issue 2021
URI https://essuir.sumdu.edu.ua/handle/123456789/85419
Publisher Sciendo
License Creative Commons Attribution 4.0 International License
Citation Sikora V., Lуndіn M., Hyriavenko N., Moskalenko R., Lуndіna Y., Sikora K., Chyzhma R., Diachenko O., Romaniuk A. Morphological peculiarities of parasitic (Trichosomoides crassicauda) infection in rat urinary bladder. Mac Vet Rev 2021; 44 (2): i-ix. https://doi.org/10.2478/macvetrev-2021-0019
Abstract Trichosomoides crassicauda (T. crassicauda) is a parasite commonly localized in the urinary bladder (UB) of laboratory and wild rats. The presence of these helminths can influence the prediction of pathological changes in the UB. Therefore, the purpose of this research was to make a comprehensive study of the features of the morphological changes in the UB wall of white laboratory rats as a result of T. crassicauda infestation. The study was performed on male rats using histological (Hematoxyline-Eosin and Alcian Blue staining) and immunohistochemical (Ki-67, Hsp70, Hsp90α, CD3 and CD20) methods. T. crassicauda was detected in both urine and UB samples. Morphological changes were observed as disruption in urothelial cell stratification and insignificant proliferative and immune responses in the UB. Increased heat shock protein levels were observed which may suggest a natural body’s resistance to this parasite.
Appears in Collections: Наукові видання (НН МІ)

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