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|Title||Application of Polydopamine Functionalized Zinc Oxide for Glucose Biosensor Design|
Viter, Roman Vitaliiovych
photo-electrochemical glucose biosensor
ITO modified glass electrode
|Date of Issue||2021|
|License||Creative Commons Attribution 4.0 International License|
|Citation||Fedorenko, V.; Damberga, D.; Grundsteins, K.; Ramanavicius, A.; Ramanavicius, S.; Coy, E.; Iatsunskyi, I.; Viter, R. Application of Polydopamine Functionalized Zinc Oxide for Glucose Biosensor Design. Polymers 2021, 13, 2918. https:// doi.org/10.3390/polym13172918|
Zinc oxide (ZnO) nanostructures are widely used in optical sensors and biosensors. Functionalization of these nanostructures with polymers enables optical properties of ZnO to be tailored. Polydopamine (PDA) is a highly biocompatible polymer, which can be used as a versatile
coating suitable for application in sensor and biosensor design. In this research, we have grown
ZnO-based nanorods on the surface of ITO-modified glass-plated optically transparent electrodes
(glass/ITO). Then the deposition of the PDA polymer layer on the surface of ZnO nanorods was
performed from an aqueous PDA solution in such a way glass/ITO/ZnO-PDA structure was formed.
The ZnO-PDA composite was characterized by SEM, TEM, and FTIR spectroscopy. Then glucose
oxidase (GOx) was immobilized using crosslinking by glutaraldehyde on the surface of the ZnOPDA composite, and glass/ITO/ZnO-PDA/GOx-based biosensing structure was designed. This
structure was applied for the photo-electrochemical determination of glucose (Glc) in aqueous
solutions. Photo-electrochemical determination of glucose by cyclic voltammetry and amperometry has been performed by glass/ITO/ZnO-PDA/GOx-based biosensor. Here reported modification/functionalization of ZnO nanorods with PDA enhances the photo-electrochemical performance
of ZnO nanorods, which is well suited for the design of photo-electrochemical sensors and biosensors.
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Наукові видання (МІ)
|Fedorenko_et.al_Application_of_Polydopamine_2021.pdf||3,2 MB||Adobe PDF||2138343|
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