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Title Potential Role of Hydroxyapatite Nanocrystalline for Early Diagnostics of Ovarian Cancer
Authors Chyzhma, Ruslana Anatoliivna
Piddubnyi, Artem Mykhailovych  
Danylchenko, Serhii Mykolaiovych
Kravtsova, Olha Ivanivna
Moskalenko, Roman Andriiovych  
Keywords гідроксиапатит
гидроксиапатит
hydroxyapatite
кальцифікати
кальцификаты
calcification
рак яєчника
рак яичников
ovarian cancer
рання діагностика
ранняя диагностика
early diagnostics
Type Article
Date of Issue 2021
URI https://essuir.sumdu.edu.ua/handle/123456789/85468
Publisher MDPI
License Creative Commons Attribution - NonCommercial - NoDerivatives 4.0 International
Citation Chyzhma, R., Piddubnyi, A., Danilchenko, S., Kravtsova, O., Moskalenko, R. Potential Role of Hydroxyapatite Nanocrystalline for Early Diagnostics of Ovarian Cancer. Diagnostics 2021, 11, 1741. https://doi.org/10.3390/diagnostics11101741
Abstract Calcification is one of the clinical and morphological manifestations of ovarian tumors and it begins at the initial stages of carcinogenesis. Thus, this process can be used for the early diagnostics of some malignant ovarian tumors. We compared the results of ultrasound and histology and found that calcifications of a size less than 200 µm are not detected by ultrasound. These calcified structures are round fragile particles of different sizes. In the EDX (Energy-dispersive X-ray spectroscopy) spectra, the main lines were from Ca and P, and the ratio of these elements corresponds to hydroxyapatite. Thus, we established that hydroxyapatite is the main mineral component of ovarian psammoma bodies and could be used for early diagnostics of ovarian malignant neoplasia
Appears in Collections: Наукові видання (МІ)

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