Peculiarities of thyroid status of preschool children with acute bronchitis

Abstract

The aim: The aim of this study was to determine the characteristics of thyroid status (thyroid hormone, total and free fractions of triiodothyronine and thyroxine, reversible triiodothyronine, antibodies to thyroperoxidase) of preschool children with acute bronchitis. Materials and methods: We examined 135 preschool children (from 3 to 6 years old) with acute bronchitis (main group) and 28 apparently healthy subjects who were in the control group. It used clinical-anamnestic, laboratory and instrumental research methods. Evaluation of the course of acute bronchitis was carried out in the acute period of the disease. All results were statistically processed using the SPSS 26 package. Results: In 33 % of patients with acute bronchitis there are subclinical abnormalities of thyroid hormones, which manifest themselves in the form of euthyroid sick syndrome. Namely, we found an increased concentration of reversible triiodothyronine in the serum, as well as a decrease in total triiodothyronine and its free fraction. Conclusions: In patients with acute bronchitis in almost every third case there are functional shifts in hormonal status, which are manifested in the form of the first variant of the euthyroid sick syndrome.