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| Title | Evaluation of methotrexate toxicity |
| Authors |
Riabenko, Tetiana Vasylivna
Hula, Viktoriia Ivanivna
Korenkov, Oleksii Volodymyrovych
Ponyrko, Alina Oleksiivna
Teslyk, Tetiana Petrivna
Dmytruk, Serhii Mykolaiovych
Illiashenko, Viacheslav Yuriiovych
Illiashenko, Viacheslav Yu. Dudchenko, Yevhenii Serhiiovych
|
| ORCID |
http://orcid.org/0000-0003-2740-389X http://orcid.org/0000-0003-3869-5162 http://orcid.org/0000-0002-1314-5642 http://orcid.org/0000-0002-1799-7789 http://orcid.org/0000-002-5832-7415 http://orcid.org/0000-0001-6434-2817 http://orcid.org/0000-0002-9929-1287 http://orcid.org/0000-0002-1737-1735 |
| Keywords |
methotrexate toxisity side effects clinical evaluation bone marrow disease teratogenesis digestive system disease embryotoxicity skin disease lung disease liver disease kidney disease |
| Type | Article |
| Date of Issue | 2023 |
| URI | https://essuir.sumdu.edu.ua/handle/123456789/95266 |
| Publisher | Izdatel'stvo Elm |
| License | Creative Commons Attribution 4.0 International License |
| Citation | Riabenko T. V., Hula V. I., Korenkov O. V., Ponyrko A. A., Teslyk T. P. et al. Evaluation of methotrexate toxicity. Azerbaijan Medical Journal. 2023;(4).141-146. DOI: 10.34921/amj.2023.4.020. |
| Abstract |
The article analyzes literary sources on the study of the toxic effects of methotrexate in the treatment of various diseases and examines scientific data on methods of preventing their development. According to the literary information, the main toxic effects of methotrexate manifest as damage to the liver, kidneys, bone marrow, lungs, digestive system, and skin. Methotrexate exhibits pronounced embryotoxic and teratogenic effects. Monitoring of blood test parameters and selection of an optimal dose will minimize methotrexate toxic effects and help in achieving success in the treatment. |
| Appears in Collections: |
Наукові видання (НН МІ) |
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| File | Size | Format | Downloads |
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| Riabenko_methotrexate_2023.pdf | 373,49 kB | Adobe PDF | 3 |
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