Level of bronchial asthma control with regard to GLN27GLU polymorphism in the β2-adrenergic receptor gene
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Date
2017
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Sumy State University
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Abstract
The aim of our research was to identify asthma control level with regard to Gln27Glu polymorphism in the ADRB2 gene. Materials and methods. We examined 195 with bronchial asthma patients and 95 apparently healthy individuals. Patients with BA were divided into 3 groups depending on the genotypes for Gln27Glu polymorphism in the ADRB2 gene. Asthma control was assessed by means of Asthma Control Questionnaire-5 (ACQ-5) and respiratory function evaluation. Gln27Glu (rs1042714) polymorphism in the ADRB2 gene was detected using polymerase chain reaction. Statistical analysis was performed using SPSS– 21 program.
Keywords
бронхіальна астма, бронхиальная астма, bronchial asthma, поліморфізм гена, полиморфизм гена, gene polymorphism
Citation
Prystupa, L.N. Level of bronchial asthma control with regard to Gln27Glu polymorphism in the B2-adrenergic receptor gene [Текст] / L.N. Prystupa, A.V. Bondarkova // Перспективи розвитку медичної науки і освіти : збірник тез доповідей Всеукраїнської науково-методичної конференції, присвяченої 25-річчю Медичного інституту Сумського державного університету, м. Суми, 16-17 листопада 2017 р. – Суми : СумДУ, 2017. – P. 114.