Association of Arg389Gly polymorphism of ADRβ1 gene and T393C of GNAS1 gene with risk of development of acute coronary syndrome in patients with arterial hypertension
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2020
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Lithuanian University of Health Sciences
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Abstract
In our study, we discovered the relationship of the Arg389Gly polymorphism of the ADRβ1 gene and the T393C polymorphism of the GNAS1 gene with the risk of ACS development in the Ukrainian population. Carriers of the Arg389 allele of the polymorphism of the ADRβ1 gene and the C393 allele of the polymorphism of the GNAS1 gene showed a higher risk of ACS development relative to the opposite alleles in these gene polymorphisms.
Keywords
артеріальна гіпертензія, артериальная гипертензия, arterial hypertension, гострий коронарний синдром, острый коронарный синдром, acute coronary syndrome, поліморфізм генів, полиморфизм генов, gene polymorphism
Citation
Association of Arg389Gly polymorphism of ADRβ1 gene and T393C of GNAS1 gene with risk of development of acute coronary syndrome in patients with arterial hypertension / I.O. Dudchenko, L.N. Prystupa, H.A. Fadieieva, et al. // Medicina (Kaunas). - 2020. - V. 56. - P. 202.