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Title Mesoporous Silica and Composite Nanostructures for Theranostics
Authors Khanadeev, V.A.
Khlebtsov, B.N.
Terentyuk, G.S.
Chumakov, D.S.
Basko, M.V.
Bucharskaya, A.B.
Genina, E.A.
Bashkatov, A.N.
Khlebtsov, N.G.
ORCID
Keywords Mesoporous silica
Nanoparticles
Nanocomposites
Theranostics
Photodynamic therapy
Type Conference Papers
Date of Issue 2013
URI http://essuir.sumdu.edu.ua/handle/123456789/35481
Publisher Sumy State University
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Citation Mesoporous Silica and Composite Nanostructures for Theranostics [Текст] / V.A. Khanadeev, B.N. Khlebtsov, G.S. Terentyuk et al. // Nanomaterials: Applications & Properties (NAP-2013) : 3-nd International conference, Alushta, the Crimea, September 16-21, 2013 / Edited by: A. Pogrebnjak. - Sumy : Sumy State University, 2013. - V.2, No4. - 04NABM25
Abstract We discus methods for fabrication of silica and composite nanoparticles, which can be used in various biomedical applications. The most promising types of such nanostructures are hollow silica nanosheres, sil-ica coated plasmon-resonant nanoparticles (gold nanorods and gold-silver nanocages) and nanorattles. Mesoporous silica shell can be doped by desirable targeting molecules. Here we present the results of for-mation of nanocomposites composed of gold nanorods and double-layer silica shell. The secondary mesopo-rous silica shell is doped with a photosensitizer (hematoporphyrine in our case). We demonstate some of promising theranostics applications of these nanocomposites for bioimaging and in vivo therapy of tumors. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/35481
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