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Title | Assessment of cardiovascular risk in patients with Type 2 diabetes mellitus and associated obesity and ways of its correction |
Authors |
Griadil, T.I.
Chopey, I.V. Chubirko, K.I. Hechko, M.M. Rumaneh, W. |
ORCID | |
Keywords |
type 2 diabetes mellitus obesity treatment diagnostics dapaglifloflozin cardiovascular risk |
Type | Article |
Date of Issue | 2021 |
URI | https://essuir.sumdu.edu.ua/handle/123456789/84790 |
Publisher | Aluna Publishing |
License | Creative Commons Attribution - NonCommercial - NoDerivatives 4.0 International |
Citation | Griadil TI, Chopey IV, Chubirko KI, Hechko MM, Rumaneh W. Assessment of cardiovascular risk in patients with Type 2 diabetes mellitus and associated obesity and ways of its correction. Wiadomosci lekarskie. 2021;74(4):998-1002. doi: 10.36740/WLek202104135. |
Abstract |
The aim: To analyze and calculate CVR in patients with T2DM and concomitant obesity.
Materials and methods: The selection of patients was carried out based on the Uzhhorod District Clinical Hospital, in the period from November 2016 to January 2020. All
patients were divided into 3 groups: 1 (n=93) with T2DM and concomitant obesity, 2 (n=87) with T2DM, 3 (n=39) with obesity. The treatment period lasted 1 year and included
dosed exercise for at least 30 minutes per day and dietary recommendations. Patients in groups 1 and 2 received metformin 850 mg twice daily in combination with dapagliflozin
10 mg once daily. CVR was determined at the time of enrollment and after 1 year of treatment using: American College of Cardiology / American Heart Association Guideline on
the Assessment of Cardiovascular Risk (2013) (ASCVD Risk) and Framingham Risk Score (FRS).
Results: The data obtained as a result of the study revealed the highest CVR in patients of group 1, in contrast to group 2 and 3 (p<0.05). After 1 year of complex treatment,
CVR indicators were statistically significantly reduced in all experimental groups (p<0.05).
Conclusions: Determining CVR parameters and exposure to them within 10 years can remove unwanted cardiovascular complications. |
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